Interpretation of differential gene expression results of RNA-seq data: review and integration

A McDermaid, B Monier, J Zhao, B Liu… - Briefings in …, 2019 - academic.oup.com
Differential gene expression (DGE) analysis is one of the most common applications of RNA-
sequencing (RNA-seq) data. This process allows for the elucidation of differentially …

Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology

AS Thind, I Monga, PK Thakur, P Kumari… - Briefings in …, 2021 - academic.oup.com
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNA sequencing …

Qualimap 2: advanced multi-sample quality control for high-throughput sequencing data

K Okonechnikov, A Conesa, F García-Alcalde - Bioinformatics, 2016 - academic.oup.com
Motivation: Detection of random errors and systematic biases is a crucial step of a robust
pipeline for processing high-throughput sequencing (HTS) data. Bioinformatics software …

Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping

A Sas-Chen, JM Thomas, D Matzov, M Taoka… - Nature, 2020 - nature.com
Abstract N 4-acetylcytidine (ac4C) is an ancient and highly conserved RNA modification that
is present on tRNA and rRNA and has recently been investigated in eukaryotic mRNA …

[HTML][HTML] Macrophages promote anti-androgen resistance in prostate cancer bone disease

XF Li, C Selli, HL Zhou, J Cao, S Wu, RY Ma… - Journal of Experimental …, 2023 - rupress.org
Metastatic castration-resistant prostate cancer (PC) is the final stage of PC that acquires
resistance to androgen deprivation therapies (ADT). Despite progresses in understanding of …

microRNAs in the same clusters evolve to coordinately regulate functionally related genes

Y Wang, J Luo, H Zhang, J Lu - Molecular biology and evolution, 2016 - academic.oup.com
MicroRNAs (miRNAs) are endogenously expressed small noncoding RNAs. The genomic
locations of animal miRNAs are significantly clustered in discrete loci. We found duplication …

[HTML][HTML] Robustness of differential gene expression analysis of RNA-seq

A Stupnikov, CE McInerney, KI Savage… - Computational and …, 2021 - Elsevier
Abstract RNA-sequencing (RNA-seq) is a relatively new technology that lacks
standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis …

Schwann cells in the subcutaneous adipose tissue have neurogenic potential and can be used for regenerative therapies

R Stavely, R Hotta, N Picard, AA Rahman… - Science translational …, 2022 - science.org
Stem cell therapies for nervous system disorders are hindered by a lack of accessible
autologous sources of neural stem cells (NSCs). In this study, neural crest–derived Schwann …

Different miRNA expression profiles between human breast cancer tumors and serum

J Zhu, Z Zheng, J Wang, J Sun, P Wang, X Cheng… - Frontiers in …, 2014 - frontiersin.org
A bunch of microRNAs (miRNAs) have been demonstrated to be aberrantly expressed in
cancer tumor tissue and serum. The miRNA signatures identified from the serum samples …

[HTML][HTML] A pH/enzyme dual responsive PMB spatiotemporal release hydrogel promoting chronic wound repair

L Dong, C Huang, B Zhao, G Hu… - Journal of …, 2023 - jnanobiotechnology.biomedcentral …
Suppressing persistent multidrug-resistant (MDR) bacterial infections and excessive
inflammation is the key for treating chronic wounds. Therefore, developing a …