Primary ovarian insufficiency (POI) is a rare gynecological condition. This disease causes
menstrual disturbances, infertility, and various health problems. Historically, hormone …

Patients with childhood, adolescent, and young adult cancer who will be treated with
gonadotoxic therapies are at increased risk for infertility. Many patients and their families …

Development of early follicles, especially the activation of primordial follicles, is strictly
modulated by a network of signaling pathways. Recent advance in ovarian physiology has …

Purpose The purpose of this study was to summarize the latest advances and successes in
the field of ovarian tissue cryopreservation while identifying gaps in current knowledge that …

Cancer treatment is the most frequent cause of reduced fertility in cancer patients, with up to
80% of survivors affected. None of the established or experimental fertility preservation …

Many prepubertal girls and young women suffer from premature ovarian insufficiency
induced by chemotherapy given for treatment of cancer and autoimmune diseases …

Fertility preservation in the young cancer survivor is recognized as a key survivorship issue
by the American Society of Clinical Oncology and the American Society of Reproductive …

Background After ovarian tissue transplantation, ischemia-reperfusion injury and free
radicals cause follicle depletion and apoptosis. Therefore, the use of antioxidants to reduce …

Primordial follicle activation is a process in which individual primordial follicles leave their
dormant state and enter a growth phase. While existing hormone stimulation strategies …

Introduction With increasing numbers of adult female survivors of childhood cancers due to
advances in early diagnosis and treatment, the issue of preserving the reproductive potential …