Most biological processes are initiated or mediated by the association of ligands and
proteins. This work studies multistep, ligand–protein association processes by Brownian …

Today, graph theory represents one of the most important modeling techniques in biology.
One of the most important applications is in the study of metabolic networks. During …

Protein engineering strategies are often guided by our understanding of how the structure of
a protein determines its function. However, our understanding is generally restricted to small …

Due to the life cycle complexity of Schistosoma japonicum and the characteristics of
schistosomias is immuno-epidemiology, it is very challenging to give a group of certain rules …

Today, graph theory represents one of the most important modeling techniques in biology.
One of the most important applications is in the study of metabolic networks. During …

The diffusion of ligands and proteins was proposed to be guided by chreodes in water
organized by protein‐surface side chains with varying hydropathic states. These chreodes …

Models of water in the presence of amino acid side chains have revealed significant
variability in the local water structure, reflecting the variations in the hydropathic states of the …

Lattice models have been previously used to model ligand diffusion on protein surfaces.
Using such models, it has been shown that the presence of pathways (or 'chreodes') of …

This review article presents 3 theories related to ligand diffusion, general anesthesia and
sleep. The first theory describes the diffusion of molecules across a protein surface to a …

The concept of the presence of passageways, chreodes, created by the influence of the
hydropathic states of amino acid side chains on the surface water of proteins, has been …