Therapeutic potential of SOX family transcription factors in osteoarthritis

Y Huang, Z Wang - Annals of Medicine, 2025 - Taylor & Francis
Background As the worldwide population ages, osteoarthritis has significantly increased.
This musculoskeletal condition has become a pressing global health issue and thus …

[HTML][HTML] Hedgehog Pathway Is a Regulator of Stemness in HER2-Positive Trastuzumab-Resistant Breast Cancer

I Er, ABB Er - International Journal of Molecular Sciences, 2024 - pmc.ncbi.nlm.nih.gov
HER2 overexpression occurs in 20–30% of breast cancers and is associated with poor
prognosis. Trastuzumab is a standard treatment for HER2-positive breast cancer; however …

LncRNA‑p21 promotes chondrocyte apoptosis in osteoarthritis by acting as a sponge for miR‑451

L Tang, J Ding, G Zhou, Z Liu - Molecular Medicine …, 2018 - spandidos-publications.com
Osteoarthritis (OA) is the most common type of arthritis, and remains to be social and
medical challenge. Thus, identifying novel molecular targets is important for the prevention …

Adenovirus 5 produces obesity and adverse metabolic, morphological, and functional changes in the long term in animals fed a balanced diet or a high-fat diet: A …

DA Montes-Galindo, AC Espiritu-Mojarro, V Melnikov… - Archives of …, 2019 - Springer
Abstract Adenovirus 5 (Ad-5) infection is a common cause of acute respiratory infections and
the main vector used in gene therapy. There are few studies on the relationship of Ad-5 to …

A phase I–II controlled randomized trial using a promising novel cell-free formulation for articular cartilage regeneration as treatment of severe osteoarthritis of the …

I Delgado-Enciso, J Paz-Garcia… - European journal of …, 2018 - Springer
Background A promising novel cell-free bioactive formulation for articular cartilage
regeneration, called BIOF2, has recently been tested in pre-clinical trials. The aim of the …

Efficacy of neutral electrolyzed water vs. common topical antiseptics in the healing of full‑thickness burn: Preclinical trial in a mouse model

I Delgado-Enciso… - Biomedical …, 2024 - spandidos-publications.com
Burn injuries impose challenges such as infection risk, pain management, fluid loss,
electrolyte imbalance and psychological and emotional impact, on healthcare professionals …

Patient-reported health outcomes for severe knee osteoarthritis after conservative treatment with an intra-articular cell-free formulation for articular cartilage …

I Delgado-Enciso… - Experimental and …, 2019 - spandidos-publications.com
Osteoarthritis (OA) is a major public health problem characterized by joint pain, fatigue,
functional limitation and decreased quality of life of the patient, which results in increased …

A novel cell-free formulation for the treatment of knee osteoarthritis generates better patient-reported health outcomes in more severe cases

I Delgado-Enciso, J Paz-Garcia… - Journal of …, 2020 - journals.sagepub.com
Background: The bioactive cell-free formulation (BIOF2) for cartilage regeneration has
shown a major therapeutic response in severe knee osteoarthritis. However, its effect on …

МОРФОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА СУСТАВНОГО ХРЯЩА У ЛЮДЕЙ ЗРЕЛОГО И ПОЖИЛОГО ВОЗРАСТА

ШМ Ахмедов, АП Ефимов, МЮ Акрамова… - Новый день в …, 2020 - elibrary.ru
Изучены суставной хрящ коленного сустава (суставной хрящ дистальной части
бедренной кости и проксимальной части большеберцовой кости) с применением …