Furo [3, 2-c] coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms

I Cortés, LJ Cala, ABJ Bracca, TS Kaufman - RSC advances, 2020 - pubs.rsc.org
The isolation, biological activity and synthesis of natural furo [3, 2-c] coumarins are
presented, covering mainly the developments in the last 35 years. The most relevant …

Eugenol, a promising building block for biobased polymers with cutting-edge properties

R Morales-Cerrada, S Molina-Gutierrez… - …, 2021 - ACS Publications
Biobased materials, derived from biomass building blocks, are essential in the pursuit of
sustainable materials. Eugenol, a natural phenol obtained from clove oil, but also from lignin …

Regioselectivity in the Nitration of Eugenol Is Independent of Inorganic Reagents: An Experimental and Theoretical Investigation with Synthetic and Mechanistic …

JR Cardoso Barbosa, MH Queiroz… - The Journal of …, 2023 - ACS Publications
In this study, we reinvestigated the straightforward nitration of eugenol using traditional
reagents and bismuth nitrate. NMR analysis of the obtained products revealed that the …

Total synthesis of aaptamine, demethyloxyaaptamine, and their 3-alkylamino derivatives

Y Gao, F Yang, F Sun, L Liu, B Liu, SP Wang… - Organic …, 2019 - ACS Publications
A simple and efficient synthetic route for preparing the benzonaphthyridine framework is
reported. Only seven steps are needed for the assembly of 3-alkylamino aaptamine from …

A convenient and eco-friendly cerium (III) chloride-catalysed synthesis of methoxime derivatives of aromatic aldehydes and ketones

I Cortés, TS Kaufman… - Royal Society Open …, 2018 - royalsocietypublishing.org
The use of CeCl3· 7H2O as an efficient and eco-friendly promoter for the convenient
synthesis of methoximes derived from aromatic aldehydes and ketones, is reported. The …

First total synthesis of ampullosine, a unique isoquinoline alkaloid isolated from Sepedonium ampullosporum, and of the related permethylampullosine

DF Vargas, EL Larghi, TS Kaufman - RSC advances, 2019 - pubs.rsc.org
A straightforward and convenient approach toward the first total synthesis of ampullosine, a
structurally unique 3-methylisoquinoline alkaloid isolated from Sepedonium ampullosporum …

Step-Economic Total Synthesis of Melosatin A from Eugenol

SJ Bolivar Ávila, GN Ledesma, TS Kaufman… - ACS …, 2023 - ACS Publications
An efficient and straightforward route toward the isatin-type natural product melosatin A is
reported, employing a trisubstituted aniline as a key intermediate. The latter was synthesized …

Aromatic ring substituted aaptamine analogues as potential cytotoxic agents against extranodal natural killer/T-cell lymphoma

F Yang, Y Gao, YT Chang, Y Zou… - Journal of Natural …, 2020 - ACS Publications
A chemical modification study was conducted on the marine natural product aaptamine (1),
isolated from the marine sponge Aaptos aaptos. Thirty new derivatives substituted by …

[HTML][HTML] Step-Economic Total Synthesis of Melosatin A from Eugenol

SJB Ávila, GN Ledesma, TS Kaufman, SA Testero… - ACS …, 2023 - ncbi.nlm.nih.gov
An efficient and straightforward route toward the isatin-type natural product melosatin A is
reported, employing a trisubstituted aniline as a key intermediate. The latter was synthesized …

Rhodium(III)-Catalyzed Oxidative Annulation of 4-Aminoquinolines and Acrylate through Two Consecutive C(sp2)–H Activations

J Liu, Y Gao, Y Zhu, J Zhu, C Wang, X Rui, K Yang… - Organic …, 2020 - ACS Publications
The C–H annulation of the five-position of quinolines and acrylates to afford heterocycles is
an active field of research in organic synthesis. Herein the annulation of 4-aminoquinolines …