A celebrated and controversial hypothesis suggests that some biological systems—parts,
aspects, or groups of them—may extract important functional benefits from operating at the …

Boolean network models are one of the simplest models to study complex dynamic behavior
in biological systems. They can be applied to unravel the mechanisms regulating the …

The coordinated expression of the different genes in an organism is essential to sustain
functionality under the random external perturbations to which the organism might be …

Molecular mechanisms of health and disease are often represented as systems biology
diagrams, and the coverage of such representation constantly increases. These static …

The hypothesis that many living systems should exhibit near-critical behavior is well
motivated theoretically, and an increasing number of cases have been demonstrated …

Abstract Systems that exhibit complex behaviours are often found in a particular dynamical
condition, poised between order and disorder. This observation is at the core of the so …

Accumulating experimental evidence suggests that the gene regulatory networks of living
organisms operate in the critical phase, namely, at the transition between ordered and …

Fuzzy Cognitive Maps (FCMs) are a convenient tool for modeling and simulating dynamic
systems. FCMs were applied in a large number of diverse areas and have already gained …

The asymptotic dynamics of random Boolean networks subject to random fluctuations is
investigated. Under the influence of noise, the system can escape from the attractors of the …

Systems poised at a dynamical critical regime, between order and disorder, have been
shown capable of exhibiting complex dynamics that balance robustness to external …