[HTML][HTML] The obesity-autophagy-cancer axis: Mechanistic insights and therapeutic perspectives
Autophagy, a self-degradative process vital for cellular homeostasis, plays a significant role
in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex …
in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex …
[HTML][HTML] Immune checkpoints between epithelial-mesenchymal transition and autophagy: A conflicting triangle
Inhibitory immune checkpoint (ICP) molecules are pivotal in inhibiting innate and acquired
antitumor immune responses, a mechanism frequently exploited by cancer cells to evade …
antitumor immune responses, a mechanism frequently exploited by cancer cells to evade …
Transforming Growth Factor Beta and Alveolar Rhabdomyosarcoma: A Challenge of Tumor Differentiation and Chemotherapy Response
B Bhushan, R Iranpour, A Eshtiaghi… - International Journal of …, 2024 - mdpi.com
Alveolar rhabdomyosarcoma (ARMS), an invasive subtype of rhabdomyosarcoma (RMS), is
associated with chromosomal translocation events resulting in one of two oncogenic fusion …
associated with chromosomal translocation events resulting in one of two oncogenic fusion …
Characterization of a pleomorphic rhabdomyosarcoma cell line
S Stickler, C Lang, M Rieche, MT Eggerstorfer… - Scientific Reports, 2025 - nature.com
Pleomorphic rhabdomyosarcoma (PRMS) is an extremely rare soft tissue tumor with dismal
prognosis that has a higher incidence in adults compared to the other RMS subtypes. The …
prognosis that has a higher incidence in adults compared to the other RMS subtypes. The …
From standard therapies to monoclonal antibodies and immune checkpoint inhibitors–an update for reconstructive surgeons on common oncological cases
L Knoedler, L Huelsboemer, K Hollmann… - Frontiers in …, 2024 - frontiersin.org
Malignancies represent a persisting worldwide health burden. Tumor treatment is commonly
based on surgical and/or non-surgical therapies. In the recent decade, novel non-surgical …
based on surgical and/or non-surgical therapies. In the recent decade, novel non-surgical …
[HTML][HTML] Targeting PERK and GRP78 in colorectal cancer: Genetic insights and novel therapeutic approaches
Colorectal cancer (CRC) ranks among the leading causes of cancer-related deaths
worldwide. Enhancing CRC diagnosis and prognosis requires the development of improved …
worldwide. Enhancing CRC diagnosis and prognosis requires the development of improved …
[HTML][HTML] Targeting NFE2L2/GPX4 signaling pathway: Therapeutic potential of arsenic sulfide-induced ferroptosis in combating rhabdomyosarcoma
Y Cai, S Lu, C Zhu, T Kang, Z Liu, R Huang… - International …, 2024 - Elsevier
Rhabdomyosarcoma (RMS) stands as the most prevalent soft-tissue sarcoma in children,
encompassing subtypes such as embryonal, alveolar, and pleomorphic [1],[2],[3]. Standard …
encompassing subtypes such as embryonal, alveolar, and pleomorphic [1],[2],[3]. Standard …
[HTML][HTML] Phospholipase Cδ-4 (PLCδ4) Acts as a Nuclear Player to Influence Cyclin B Expression in the Embryonal Rhabdomyosarcoma Cell Lines RD and A204
Rhabdomyosarcoma (RMS), the most common form of sarcoma typical of pediatric age,
arises from the malignant transformation of the mesenchymal precursors that fail to …
arises from the malignant transformation of the mesenchymal precursors that fail to …
[HTML][HTML] Alveolar Rhabdomyosarcoma of Nasopharynx and Paranasal Sinuses in Children Diagnosis and Treatment—Review of the Literature and Case Report
C Mârțu, ȘD Tîrnovanu, I Mârțu, D Ferariu, D Mârțu… - Medicina, 2025 - mdpi.com
Alveolar rhabdomyosarcoma (aRMS) is a rare pediatric malignant tumor with a poor
prognosis, particularly when located in the rhinopharynx and sphenoidal floor, which …
prognosis, particularly when located in the rhinopharynx and sphenoidal floor, which …
Contemporary preclinical mouse models for pediatric rhabdomyosarcoma: from bedside to bench to bedside
I Martynov, L Dhaka, B Wilke, P Hoyer… - Frontiers in …, 2024 - frontiersin.org
Background Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue
malignancy, characterized by high clinicalopathological and molecular heterogeneity …
malignancy, characterized by high clinicalopathological and molecular heterogeneity …