FunCoup 6: advancing functional association networks across species with directed links and improved user experience
Abstract FunCoup 6 (https://funcoup. org) represents a significant advancement in global
functional association networks, aiming to provide researchers with a comprehensive view …
functional association networks, aiming to provide researchers with a comprehensive view …
Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression
Exposure to an acute stressor triggers a complex cascade of neurochemical events in the
brain. However, deciphering their individual impact on stress-induced molecular changes …
brain. However, deciphering their individual impact on stress-induced molecular changes …
The Identification of Potential Anti-Depression/Anxiety Drug Targets by Stress-Induced Rat Brain Regional Proteome and Network Analyses
N Liu, J Tu, F Yi, X Zhang, X Zhong, L Wang… - Neurochemical …, 2024 - Springer
Depression and anxiety disorders are prevalent stress-related neuropsychiatric disorders
and involve multiple molecular changes and dysfunctions across various brain regions …
and involve multiple molecular changes and dysfunctions across various brain regions …
Multi-omics regulatory network inference in the presence of missing data
JD Henao, M Lauber, M Azevedo… - Briefings in …, 2023 - academic.oup.com
A key problem in systems biology is the discovery of regulatory mechanisms that drive
phenotypic behaviour of complex biological systems in the form of multi-level networks …
phenotypic behaviour of complex biological systems in the form of multi-level networks …
[HTML][HTML] Multiomics Analysis of the Molecular Response to Glucocorticoids: Insights Into Shared Genetic Risk From Psychiatric to Medical Disorders
J Knauer-Arloth, A Hryhorzhevska, EB Binder - Biological Psychiatry, 2024 - Elsevier
Background Alterations in the effects of glucocorticoids have been implicated in mediating
some of the negative health effects associated with chronic stress, including increased risk …
some of the negative health effects associated with chronic stress, including increased risk …
From multi-omics data to global association networks: Application to disease module finding and pathway analysis
D Buzzao - 2024 - diva-portal.org
This thesis explores how bioinformatics advances the study of complex diseases by
providing system-level models that capture intricate gene-protein interactions. Traditional …
providing system-level models that capture intricate gene-protein interactions. Traditional …
The locus coeruleus noradrenergic system in stress: Shaping the pupillary and transcriptomic stress response
M Privitera - 2023 - research-collection.ethz.ch
In an ever-changing environment, we are constantly presented with new challenging and
stressful situations. Within all organisms, specific molecular, physiological and behavioral …
stressful situations. Within all organisms, specific molecular, physiological and behavioral …
FKBP51 in a dynamic environment
L van Doeselaar - 2023 - pure.mpg.de
Mental health disorders are a pressing global health-threat, affecting millions of people
world-wide, which has already cost the world economy over 2.5 trillion dollars, making it a …
world-wide, which has already cost the world economy over 2.5 trillion dollars, making it a …
FKBP51 in a dynamic environment
L Doeselaar - 2023 - edoc.ub.uni-muenchen.de
Mental health disorders are a pressing global health-threat, affecting millions of people
world-wide, which has already cost the world economy over 2.5 trillion dollars, making it a …
world-wide, which has already cost the world economy over 2.5 trillion dollars, making it a …
Neurodevelopment under the prism of environmental challenges
A Krontira - 2022 - edoc.ub.uni-muenchen.de
Prenatal development affects adult health. Exposures to a variety of prenatal environmental
factors have important effects on fetal development and, in turn, are extensively associated …
factors have important effects on fetal development and, in turn, are extensively associated …