Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Diabetic nephropathy (DN), a sterile inflammatory disease, is a serious complication of
diabetes mellitus. However, recent evidence indicates that pyroptosis, a new term for pro …

Diabetic wound is one of the complications of diabetes and is not easy to heal. It often
evolves into chronic ulcers, and severe patients will face amputation. Compared with normal …

Pyroptosis is mainly considered a gasdermin-regulated cell death mechanism characterized
by cellular lysis and the release of several pro-inflammatory factors. Nowadays, pyroptosis …

Pancreatic beta-cell death has been established as a critical mediator in the progression of
type 1 and type 2 diabetes mellitus. Beta-cell death is associated with exacerbating …

Diabetes mellitus (DM) and its complications have become an important global public health
issue, affecting human health and negatively impacting life and lifespan. Pyroptosis is a …

Diabetic peripheral neuropathy (DPN) is a complication of diabetes mellitus that lacks
specific treatment, its high prevalence and disabling neuropathic pain greatly affects …

Pyroptosis, also known as cellular inflammatory necrosis, is a programmed cell death
mediated by the Gasdermin family of proteins. The mechanisms by which pyroptosis occurs …

Objective: Diabetes mellitus is a chronic progressive inflammatory metabolic disease with
pancreatic β-cells dysfunction. The present study aimed to investigate whether miR-17-5p …

Background Pyroptosis is crucial for controlling various immune cells. However, the role of
allergen-induced CD11c+ dendritic cell (DC) pyroptosis in allergic rhinitis (AR) remains …