The effect of music-based intervention on general cognitive and executive functions, and episodic memory in people with mild cognitive impairment and dementia: a …

E Ito, R Nouchi, J Dinet, CH Cheng, BS Husebø - Healthcare, 2022 - mdpi.com
Background: Music-based intervention has been used as first-line non-pharmacological
treatment to improve cognitive function for people with mild cognitive impairment (MCI) or …

Traditional uses, phytochemistry, transformation of ingredients and pharmacology of the dried seeds of Raphanus sativus L.(Raphani Semen), A comprehensive …

L Gao, H Li, B Li, H Shao, X Yu, Z Miao, L Zhang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Raphani Semen (Lai Fu-zi in Chinese, RS), the
dried seeds of Raphanus sativus L., is a traditional Chinese herbal medicine. RS has long …

Exploring the anti‐inflammatory activity of sulforaphane

K Treasure, J Harris… - Immunology and Cell …, 2023 - Wiley Online Library
Dysregulation of innate immune responses can result in chronic inflammatory conditions.
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …

Benefits of VR physical exercise on cognition in older adults with and without mild cognitive decline: a systematic review of randomized controlled trials

K Sakaki, R Nouchi, Y Matsuzaki, T Saito, J Dinet… - Healthcare, 2021 - mdpi.com
It is well known that physical exercise has beneficial effects on cognitive function in older
adults. Recently, several physical exercise programs with virtual reality (VR) have been …

Sulforaphane increase mitochondrial biogenesis-related gene expression in the hippocampus and suppresses age-related cognitive decline in mice

S Shimizu, S Kasai, H Yamazaki, Y Tatara… - International Journal of …, 2022 - mdpi.com
Sulforaphane (SFN) is a potent activator of the transcriptional factor, Nuclear Factor
Erythroid 2 (NF-E2)-Related factor 2 (NRF2). SFN and its precursor, glucoraphanin …

The role of the NRF2 pathway in maintaining and improving cognitive function

NE Gray, M Farina, P Tucci, L Saso - Biomedicines, 2022 - mdpi.com
Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a redox-sensitive transcription factor that
binds to the antioxidant response element consensus sequence, decreasing reactive …

Auditory cognitive training improves brain plasticity in healthy older adults: Evidence from a randomized controlled trial

NYS Kawata, R Nouchi, K Oba, Y Matsuzaki… - Frontiers in Aging …, 2022 - frontiersin.org
The number of older adults is increasing globally. Aging is associated with cognitive and
sensory decline. Additionally, declined auditory performance and cognitive function affect …

Transgenerational hormesis in healthy aging and antiaging medicine from bench to clinics: Role of food components

V Calabrese, N Osakabe, R Siracusa… - Mechanisms of Ageing …, 2024 - Elsevier
Neurodegenerative diseases have multifactorial pathogenesis, mainly involving
neuroinflammatory processes. Finding drugs able to treat these diseases, expecially …

The effect of cognitive training with neurofeedback on cognitive function in healthy adults: a systematic review and meta-analysis

Y Matsuzaki, R Nouchi, K Sakaki, J Dinet… - Healthcare, 2023 - mdpi.com
Background: Cognitive training aims to improve cognitive function through cognitive tasks or
training games. Neurofeedback is a technique to monitor brain signals with either visual or …

Cognitive training with neurofeedback using NIRS improved cognitive functions in young adults: evidence from a randomized controlled trial

R Nouchi, H Nouchi, J Dinet, R Kawashima - Brain sciences, 2021 - mdpi.com
(1) Background: A previous study has shown that cognitive training with neurofeedback (CT-
NF) using down-regulation improves cognitive functions in young adults. Neurofeedback …