The impact of varying the number and selection of conditions on estimated multimorbidity prevalence: a cross-sectional study using a large, primary care population …

C MacRae, M McMinn, SW Mercer, D Henderson… - PLoS …, 2023 - journals.plos.org
Background Multimorbidity prevalence rates vary considerably depending on the conditions
considered in the morbidity count, but there is no standardised approach to the number or …

The epidemiology of atopic dermatitis in older adults: a population-based study in the United Kingdom

LN Chan, A Magyari, M Ye, NA Al-Alusi, SM Langan… - PloS one, 2021 - journals.plos.org
Background Atopic dermatitis is known to be common among children, but there are few
studies examining the epidemiology across the life course. In particular, there is a paucity of …

Health conditions in adults with HIV compared with the general population: A population-based cross-sectional analysis

DR Morales, D Moreno-Martos, N Matin… - …, 2022 - thelancet.com
Background Life expectancy in adults with human immunodeficiency virus (HIV) has
increased and managing other health conditions is increasingly important for patients and …

Ethnic differences in early onset multimorbidity and associations with health service use, long-term prescribing, years of life lost, and mortality: A cross-sectional study …

F Eto, M Samuel, R Henkin, M Mahesh, T Ahmad… - PLoS …, 2023 - journals.plos.org
Background The population prevalence of multimorbidity (the existence of at least 2 or more
long-term conditions [LTCs] in an individual) is increasing among young adults, particularly …

A population-based study exploring phenotypic clusters and clinical outcomes in stroke using unsupervised machine learning approach

RK Akyea, G Ntaios, E Kontopantelis… - PLOS Digital …, 2023 - journals.plos.org
Individuals developing stroke have varying clinical characteristics, demographic, and
biochemical profiles. This heterogeneity in phenotypic characteristics can impact on …

Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005–2019), by area deprivation profile: linked electronic health records cohort …

J Lyons, A Akbari, KR Abrams, AA Lorenzo… - The Lancet Regional …, 2023 - thelancet.com
Background Understanding and quantifying the differences in disease development in
different socioeconomic groups of people across the lifespan is important for planning …

Hospital-wide natural language processing summarising the health data of 1 million patients

DM Bean, Z Kraljevic, A Shek, J Teo… - PLOS digital …, 2023 - journals.plos.org
Electronic health records (EHRs) represent a major repository of real world clinical
trajectories, interventions and outcomes. While modern enterprise EHR's try to capture data …

Prevalence of chronic pain or analgesic use in children and young people and its long-term impact on substance misuse, mental illness, and prescription opioid use: a …

A Lambarth, M Katsoulis, C Ju, A Warwick… - The Lancet Regional …, 2023 - thelancet.com
Background Epidemiological studies suggest chronic and recurrent pain affects around a
quarter of children, while 8% report intense and frequent pain. The long-term implications of …

Paediatric rotavirus vaccination, coeliac disease and type 1 diabetes in children: a population-based cohort study

T Inns, KM Fleming, M Iturriza-Gomara, D Hungerford - BMC medicine, 2021 - Springer
Background Rotavirus infection has been proposed as a risk factor for coeliac disease (CD)
and type 1 diabetes (T1D). The UK introduced infant rotavirus vaccination in 2013. We have …

Excess health care use is significantly and persistently reduced following diagnosis of late‐onset epilepsy

M Berglund, A Gonzalez‐Izquierdo, S Denaxas… - …, 2024 - Wiley Online Library
Objective The incidence of late‐onset epilepsy (LOE) is rising, and these patients may use
an excess of health care resources. This study aimed to measure pre‐/post‐diagnostic …