The importance of ongoing international surveillance for Creutzfeldt–Jakob disease

N Watson, JP Brandel, A Green, P Hermann… - Nature Reviews …, 2021 - nature.com
Creutzfeldt–Jakob disease (CJD) is a rapidly progressive, fatal and transmissible
neurodegenerative disease associated with the accumulation of misfolded prion protein in …

Chronic wasting disease of cervids: current knowledge and future perspectives

NJ Haley, EA Hoover - Annu. Rev. Anim. Biosci., 2015 - annualreviews.org
A naturally occurring transmissible spongiform encephalopathy (TSE) of mule deer was first
reported in Colorado and Wyoming in 1967 and has since spread to other members of the …

Chronic wasting disease in cervids: prevalence, impact and management strategies

NA Rivera, AL Brandt, JE Novakofski… - Veterinary Medicine …, 2019 - Taylor & Francis
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that
affects members of the cervidae family. The infectious agent is a misfolded isoform (PrPSC) …

Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD

S Hannaoui, I Zemlyankina, SC Chang, MI Arifin… - Acta …, 2022 - Springer
Prions cause infectious and fatal neurodegenerative diseases in mammals. Chronic wasting
disease (CWD), a prion disease of cervids, spreads efficiently among wild and farmed …

[HTML][HTML] The prion strain phenomenon: molecular basis and unprecedented features

R Morales, K Abid, C Soto - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
Prions are unconventional infectious agents responsible for transmissible spongiform
encephalopathies. Compelling evidences indicate that prions are composed exclusively by …

[HTML][HTML] Susceptibilities of nonhuman primates to chronic wasting disease

B Race, KD Meade-White, MW Miller… - Emerging infectious …, 2009 - ncbi.nlm.nih.gov
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion
disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven …

Transmission of elk and deer prions to transgenic mice

G Tamgüney, K Giles… - Journal of …, 2006 - Am Soc Microbiol
Chronic wasting disease (CWD) is a fatal prion disease in deer and elk. Unique among the
prion diseases, it is transmitted among captive and free-ranging animals. To facilitate studies …

[HTML][HTML] Chronic wasting disease prions in elk antler velvet

RC Angers, TS Seward, D Napier, M Green… - Emerging infectious …, 2009 - ncbi.nlm.nih.gov
Chronic wasting disease (CWD) is a contagious, fatal prion disease of deer and elk that
continues to emerge in new locations. To explore the means by which prions are transmitted …

Lack of transmission of chronic wasting disease to cynomolgus macaques

B Race, K Williams, CD Orrú, AG Hughson… - Journal of …, 2018 - Am Soc Microbiol
Chronic wasting disease (CWD) is a fatal prion disease that can infect deer, elk, and moose.
CWD was first recognized in captive deer kept in wildlife facilities in Colorado from 1967 to …

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

MK Sandberg, H Al-Doujaily… - Journal of General …, 2010 - microbiologyresearch.org
Chronic wasting disease (CWD) is a prion disease that affects free-ranging and captive
cervids, including mule deer, white-tailed deer, Rocky Mountain elk and moose. CWD …