Plants exhibit remarkable lineage plasticity, allowing them to regenerate organs that differ
from their respective origins. Such developmental plasticity is dependent on the activity of …

Stem cell-independent reprogramming of differentiated cells has recently been identified as
an important paradigm for repairing injured tissues. Following periportal injury, mature …

The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that
can regenerate any missing body part and their regenerative powers have combined with …

Regeneration requires cellular proliferation, differentiation, and other processes that are
regulated by secreted cues originating from cells in the local environment. Recent studies …

Heart regeneration is a fascinating and complex biological process. Decades of intensive
studies have revealed a sophisticated molecular network regulating cardiac regeneration in …

The common laboratory zebrafish can regenerate functional cardiac muscle after
cataclysmic damage or loss, by activating programs that direct the division of spared …

Lipid metabolism plays an instructive role in regulating stem cell state and differentiation.
However, the roles of lipid mobilization and utilization in stem cell-driven regeneration are …

Myocardial Brg1 is essential for heart regeneration in zebrafish, but it remains unknown
whether and how endothelial Brg1 plays a role in heart regeneration. Here, we found that …

Regeneration is a widely observed phenomenon by which the integrity of an organism is
recovered after damage. To date, studies on the molecular and cellular mechanisms of …

In humans, injuries and diseases can result in irreversible tissue or organ loss. This well-
known fact has prompted several basic studies on organisms capable of adult regeneration …