Post-traumatic osteoarthritis: from mouse models to clinical trials

CB Little, DJ Hunter - Nature Reviews Rheumatology, 2013 - nature.com
Osteoarthritis (OA), the most common of all arthropathies, is a leading cause of disability and
has a large (and growing) worldwide socioeconomic cost. Despite its burgeoning …

Subject-specific analysis of joint contact mechanics: application to the study of osteoarthritis and surgical planning

CR Henak, AE Anderson… - Journal of …, 2013 - asmedigitalcollection.asme.org
Advances in computational mechanics, constitutive modeling, and techniques for subject-
specific modeling have opened the door to patient-specific simulation of the relationships …

Physical validation of a patient-specific contact finite element model of the ankle

DD Anderson, JK Goldsworthy, W Li, MJ Rudert… - Journal of …, 2007 - Elsevier
A validation study was conducted to determine the extent to which computational ankle
contact finite element (FE) results agreed with experimentally measured tibio-talar contact …

Validation of a personalized ligament-constraining discrete element framework for computing ankle joint contact mechanics

M Peiffer, K Duquesne, A Van Oevelen… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective Computer simulations of joint contact mechanics have
great merit to improve our current understanding of articular ankle pathology. Owed to its …

Is elevated contact stress predictive of post‐traumatic osteoarthritis for imprecisely reduced tibial plafond fractures?

DD Anderson, C Van Hofwegen… - Journal of …, 2011 - Wiley Online Library
Despite the widely held belief that residual incongruities from intra‐articular fractures subject
the joint to contact stresses that predispose to post‐traumatic osteoarthritis (PTOA), objective …

Finite element analysis of unicompartmental knee arthroplasty

AR Hopkins, AM New, F Rodriguez-y-Baena… - Medical engineering & …, 2010 - Elsevier
Concerns over accelerated damage to the untreated compartment of the knee following
unicompartmental knee arthroplasty (UKA), as well as the relatively poor success rates …

Personalised statistical modelling of soft tissue structures in the ankle

M Peiffer, A Burssens, K Duquesne, M Last… - Computer Methods and …, 2022 - Elsevier
Background and objective Revealing the complexity behind subject-specific ankle joint
mechanics requires simultaneous analysis of three-dimensional bony and soft-tissue …

[HTML][HTML] The pathomechanical etiology of post-traumatic osteoarthritis following intraarticular fractures

DD Anderson, JL Marsh, TD Brown - The Iowa orthopaedic journal, 2011 - ncbi.nlm.nih.gov
Many intra-articular fracture patients eventually experience significant functional deficits,
pain, and stiffness from post-traumatic osteoarthritis (PTOA). Over the last several decades …

In vivo cartilage contact deformation of human ankle joints under full body weight

L Wan, RJ de Asla, HE Rubash… - Journal of orthopaedic …, 2008 - Wiley Online Library
Quantitative data on in vivo deformation of articular cartilage is important for understanding
the articular joint function and the etiology of degenerative joint diseases such as …

Regional variations of gender-specific and age-related differences in trabecular bone structure of the distal radius and tibia

M Sode, AJ Burghardt, GJ Kazakia, TM Link… - Bone, 2010 - Elsevier
Regional variation in trabecular structure across axial sections is often obscured by the
conventional global analysis, which takes an average value for the entire trabecular …