Pharmacometabolomic Approach to Investigate the Response to Metformin in Patients with Type 2 Diabetes: A Cross-Sectional Study

K Naja, N Anwardeen, M Al-Hariri, AA Al Thani… - Biomedicines, 2023 - mdpi.com
Metformin constitutes the foundation therapy in type 2 diabetes (T2D). Despite its multiple
beneficial effects and widespread use, there is considerable inter-individual variability in …

Clinical Approach to Genetic Cerebral Arteriopathy in the Adult Patient With Ischemic Stroke

EN Haddad, P Kumar, G Shearn-Nance… - Neurology …, 2024 - neurology.org
Genetic arteriopathies leading to stroke in adults constitute a diverse group of
cerebrovascular disorders with distinct etiologies, pathophysiologic mechanisms, and …

Association of Genetic Polymorphism rs 77630697 (Gly64Asp) of Multidrug and Toxin Extrusion-1 with glycemic response to metformin in patients with Type 2 …

Z Hakim, N ul Hasan, A Khan, A Waheed - Pakistan Journal of Medical …, 2024 - pjms.org.pk
Objective: To determine the relationship between Gly64Asp (rs77630697) polymorphism of
multidrug and toxin extrusion-1 (MATE-1) and therapeutic response of metformin in Type-2 …