Application prospect of calcium peroxide nanoparticles in biomedical field

X Wu, X Han, Y Guo, Q Liu, R Sun, Z Wen… - Reviews on Advanced …, 2023 - degruyter.com
In recent years, calcium peroxide (CaO2) has attracted widespread attention in the medical
community due to its excellent antitumor and antibacterial properties, and has gradually …

Peroxide mediated oxygen delivery in cancer therapy

S Khorshidi, S Younesi, A Karkhaneh - Colloids and Surfaces B …, 2022 - Elsevier
Hypoxia is a serious obstacle in cancer treatment. The aberrant vascular network as well as
the abnormal extracellular matrix arrangement results in formation of a hypoxic regions in …

Tumor microenvironment (TME)-modulating nanoreactor for multiply enhanced chemodynamic therapy synergized with chemotherapy, starvation, and photothermal …

S Hao, J Zuo, H Huang, W Li, H Guo, M Liu… - Journal of Materials …, 2023 - pubs.rsc.org
The combination of chemotherapy (CT) and chemodynamic therapy (CDT) via nanoscale
drug delivery systems has great potential for tumor therapy. Nevertheless, the low …

Hollow mesoporous calcium peroxide nanoparticles for drug-free tumor calcicoptosis therapy

H Zhou, J Yang, Z Li, J Feng, X Duan, C Yan, G Wen… - Acta Biomaterialia, 2024 - Elsevier
Abstract Calcium ions (Ca 2+) participate in the regulation of cellular apoptosis as a second
messenger. Calcium overload, which refers to the abnormal elevation of intracellular Ca 2+ …

CaO2 nanomedicines: a review of their emerging roles in cancer therapy

C He, S Zhang, X Liu, J Wang, Y Huang… - …, 2023 - iopscience.iop.org
Metal peroxide-based nanomedicines have emerged as promising theranostic agents for
cancer due to their multifunctional properties, including the generation of bioactive small …

NIR absorptive croconic acid/quercetin/CaO2 nanoplatform for tumor calcium overload therapy combined mild photothermal therapy

W Wang, J Yu, Y Lin, M Li, Y Pan, Y He, L Liu… - Biomaterials …, 2023 - Elsevier
With excellent biocompatibility, stable chemical and optical properties, small organic
molecules-based agents have always been a research hotspot in cancer photothermal …

[HTML][HTML] The progress and prospect of calcium peroxide nanoparticles in cancer therapy

S Zhang, C He, C Zhang - Journal of Drug Delivery Science and …, 2024 - Elsevier
Recent advancements in nanomedicine have sparked interest in exploring innovative
strategies for cancer therapy. Calcium peroxide nanoparticles (CaO 2 NPs) have emerged …

Thermo-Sensitive Nanoparticle-Hydrogel Composite Based on Pluronic F127 and Phycocyanin for an Enhanced Chemo-Photodynamic Antitumor Effect

J Song, R Hu, J Zhang, Y Yu, Y Zhou… - ACS Applied Polymer …, 2023 - ACS Publications
The concurrent utilization of chemotherapy and photodynamic therapy (PDT) can
successfully slow the growth of tumors while minimizing systemic toxicity. An injectable …

Combined Photothermal/Combination Chemotherapeutic Approach Using Zif-8-Supported Artesunate and Gold Nanorods

X Li, J Wang, W Li, F Xu, Y Gao, T Cui… - ACS Applied Nano …, 2024 - ACS Publications
Tumors pose a significant threat to human well-being, presenting substantial risks to lives.
Conventional approaches to cancer treatment exhibit limited efficacy in eliminating the …

Composite Nanoplatforms Based on Nanocalcium Peroxide for Cancer Treatment: From Monotherapy to Combination Therapy

X Hu, J Liu, Y Wang, B Xu, J Gongye, Y Liu… - Advanced …, 2023 - Wiley Online Library
Nano‐CaO2, with its multifunctional properties, has emerged as a promising candidate for
tumor therapy. Its ability to release Ca2+ and H2O2 into the tumor microenvironment has …