A comprehensive insight into the anti-inflammatory properties of dapsone

M Khalilzadeh, M Shayan, S Jourian, M Rahimi… - Naunyn-Schmiedeberg's …, 2022 - Springer
Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

[HTML][HTML] Dapsone, more than an effective neuro and cytoprotective drug

A Diaz-Ruiz, J Nader-Kawachi… - Current …, 2022 - ncbi.nlm.nih.gov
Background Dapsone (4, 4'-diamino-diphenyl sulfone) is a synthetic derivative of sulfones,
with the antimicrobial activity described since 1937. It is also a drug traditionally used in …

Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-α Signaling Pathways and the Suppression of Oxidative Stress …

WY Abdelzaher, SM Ahmed, NN Welson… - Frontiers in …, 2021 - frontiersin.org
Myocardial infarction (MI) is a critical condition that can happen with high doses or rapid
termination of beta blockers therapy. The study aimed to evaluate the potential anti-toxic …

Protective effect of dapsone against bleomycin-induced lung fibrosis in rat

H Yousefi-Manesh, T Noori, MH Asgardoon… - Experimental and …, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial disease of the lung tissue that
causes symptoms such as coughing and asthma. It is caused by inflammatory factors and …

Curcumin protects against renal ischemia/reperfusion injury by regulating oxidative stress and inflammatory response

X Cui, L Lin, X Sun, L Wang… - … and Alternative Medicine, 2021 - Wiley Online Library
Objective. The aim of this study was to explore the pharmacological effects of curcumin on
oxidative stress and inflammatory response of renal dysfunction induced by renal …

The effect of dapsone in testosterone enanthate-induced polycystic ovary syndrome in rat

S Shirooie, E Khaledi, AR Dehpour, T Noori… - The Journal of steroid …, 2021 - Elsevier
Background One of the most common reasons for infertility is polycystic ovary syndrome
(PCOS). PCOS is related to metabolic syndrome, weight gain, type 2 diabetes mellitus, and …

Ivermectin ameliorates bleomycin-induced lung fibrosis in male rats by inhibiting the inflammation and oxidative stress

F Habibi Razi, R Mohammad Jafari… - …, 2024 - Taylor & Francis
Background Idiopathic pulmonary fibrosis (IPF) is a pulmonary fibrotic disease characterized
by a poor prognosis, which its pathogenesis involves the accumulation of abnormal fibrous …

Isobolographic Analysis of the Cytoprotective Effect of Dapsone and Cannabidiol Alone or Combination upon Oxygen–Glucose Deprivation/Reoxygenation Model in …

M Islas-Cortez, C Ríos, J Manzanares, A Díaz-Ruiz… - Antioxidants, 2024 - mdpi.com
Oxidative stress and apoptosis cell death are critical secondary damage mechanisms that
lead to losing neighboring healthy tissue after cerebral ischemia. This study aims to …

Evaluating the protective effect of dapsone on experimental osteoarthritis models induced by MIA in male rats

K Nazari, S Hosseindoost, AR Dehpour… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives Osteoarthritis, a degenerative condition that results in significant morbidity, is
typically managed with treatments aimed at symptom relief rather than addressing the …

Sumatriptan mitigates bleomycin-induced lung fibrosis in male rats: Involvement of inflammation, oxidative stress and α-SMA

A Bahramifar, RM Jafari, M Sheibani, MA Manavi… - Tissue and Cell, 2024 - Elsevier
Introduction Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung condition that produces
symptoms including coughing which may cause by excessive accumulation of scar tissue …