Recent advances in responsive antibacterial materials: design and application scenarios

B Zhang, D Lu, H Duan - Biomaterials Science, 2023 - pubs.rsc.org
Bacterial infection is one of the leading causes of death globally, although modern medicine
has made considerable strides in the past century. As traditional antibiotics are suffering …

Research progress of nanoparticle targeting delivery systems in bacterial infections

M Jin, B He, X Cai, Z Lei, T Sun - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
Bacterial infection is a huge threat to the health of human beings and animals. The abuse of
antibiotics has led to the occurrence of bacterial multidrug resistance, which has become a …

ROS-activatable nanocomposites for CT imaging tracking and antioxidative protection of mesenchymal stem cells in idiopathic pulmonary fibrosis therapy

Y Lv, C Yu, X Li, H Bao, S Song, X Cao, H Lin… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stem cell (MSC) transplantation is emerging as a promising approach in the
treatment of idiopathic pulmonary fibrosis (IPF), while it is still impeded by several …

H2S responsive PEGylated poly (lipoic acid) with ciprofloxacin for targeted therapy of Salmonella

L Han, XW Liu, T Zang, H Ren, DS Liang, SC Bai… - Journal of Controlled …, 2022 - Elsevier
Targeted antibiotic delivery system would be an ideal solution for the treatment of
enteropathogenic infections since it avoids the excessive usage of antibiotics clinically …

Inflammation-responsive drug delivery nanosystems for treatment of bacterial-induced sepsis

VO Nyandoro, CA Omolo, EA Ismail, L Yong… - International Journal of …, 2023 - Elsevier
Sepsis, a complication of dysregulated host immune systemic response to an infection, is life
threatening and causes multiple organ injuries. Sepsis is recognized by WHO as a big …

Antibacterial and Biofilm-Eradicating Activities of pH-Responsive Vesicles against Pseudomonas aeruginosa

S Cui, J Qiao, MP Xiong - Molecular Pharmaceutics, 2022 - ACS Publications
The formation of biofilms by a microcolony of bacteria is a significant burden on the
healthcare industry due to difficulty eradicating it. In this study, pH-responsive vesicles …

Intracellular infection-responsive macrophage-targeted nanoparticles for synergistic antibiotic immunotherapy of bacterial infection

X Dai, Y Li, X Liu, Y Zhang, F Gao - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Intracellular bacteria are considered to play a key role in the failure of bacterial infection
therapy and increase of antibiotic resistance. Nanotechnology-based drug delivery carriers …

Dual‐Responsive Nanogels with Cascaded Gentamicin Release and Lysosomal Escape to Combat Intracellular Small Colony Variants for Peritonitis and Sepsis …

S Xie, Y Li, W Cao, J Peng, K Huang… - Advanced Healthcare …, 2024 - Wiley Online Library
Intracellular bacteria are the major cause of serious infections including sepsis and
peritonitis, but face great challenges in fighting against the stubborn intracellular small …

A biotin-modified and H2O2-activatable theranostic nanoplatform for enhanced photothermal and chemical combination cancer therapy

C Jian, Y Wang, H Liu, Z Yin - European Journal of Pharmaceutics and …, 2022 - Elsevier
Although synergistic effects of photothermal therapy (PTT) and chemotherapy for cancer
have been extensively investigated in previous studies, more potential strategies need to be …

Endocytosis-mediated redistribution of antibiotics targets intracellular bacteria

S Qu, K Zhu - Nanoscale, 2023 - pubs.rsc.org
The increasing emergence and dissemination of antibiotic resistance pose a severe threat to
overwhelming healthcare practices worldwide. The lack of new antibacterial drugs urgently …