Recombination, pairing, and synapsis of homologs during meiosis

D Zickler, N Kleckner - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Recombination is a prominent feature of meiosis in which it plays an important role in
increasing genetic diversity during inheritance. Additionally, in most organisms …

Control of meiotic crossovers: from double-strand break formation to designation

S Gray, PE Cohen - Annual review of genetics, 2016 - annualreviews.org
Meiosis, the mechanism of creating haploid gametes, is a complex cellular process
observed across sexually reproducing organisms. Fundamental to meiosis is the process of …

The synaptonemal complex imposes crossover interference and heterochiasmy in Arabidopsis

L Capilla-Pérez, S Durand, A Hurel… - Proceedings of the …, 2021 - National Acad Sciences
Meiotic crossovers (COs) have intriguing patterning properties, including CO interference,
the tendency of COs to be well-spaced along chromosomes, and heterochiasmy, the marked …

The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors

O Rog, S Köhler, AF Dernburg - Elife, 2017 - elifesciences.org
The synaptonemal complex (SC) is a polymer that spans~ 100 nm between paired
homologous chromosomes during meiosis. Its striated, periodic appearance in electron …

Architecture and dynamics of meiotic chromosomes

SN Ur, KD Corbett - Annual Review of Genetics, 2021 - annualreviews.org
The specialized two-stage meiotic cell division program halves a cell's chromosome
complement in preparation for sexual reproduction. This reduction in ploidy requires that in …

Superresolution expansion microscopy reveals the three-dimensional organization of the Drosophila synaptonemal complex

CK Cahoon, Z Yu, Y Wang, F Guo… - Proceedings of the …, 2017 - National Acad Sciences
The synaptonemal complex (SC), a structure highly conserved from yeast to mammals,
assembles between homologous chromosomes and is essential for accurate chromosome …

Zipping and unzipping: protein modifications regulating synaptonemal complex dynamics

J Gao, MP Colaiácovo - Trends in Genetics, 2018 - cell.com
The proteinaceous zipper-like structure known as the synaptonemal complex (SC), which
forms between pairs of homologous chromosomes during meiosis from yeast to humans …

[HTML][HTML] Dynamic architecture of DNA repair complexes and the synaptonemal complex at sites of meiotic recombination

A Woglar, AM Villeneuve - Cell, 2018 - cell.com
Meiotic double-strand breaks (DSBs) are generated and repaired in a highly regulated
manner to ensure formation of crossovers (COs) while also enabling efficient non-CO repair …

Let's get physical–mechanisms of crossover interference

L von Diezmann, O Rog - Journal of cell science, 2021 - journals.biologists.com
The formation of crossovers between homologous chromosomes is key to sexual
reproduction. In most species, crossovers are spaced further apart than would be expected if …

[HTML][HTML] Meiosis

KJ Hillers, V Jantsch, E Martinez-Perez… - WormBook: the online …, 2017 - ncbi.nlm.nih.gov
Sexual reproduction requires the production of haploid gametes (sperm and egg) with only
one copy of each chromosome; fertilization then restores the diploid chromosome content in …