Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of Gram-positive
infections including complicated skin and skin structure infections, right-sided infective …

Staphylococcus aureus is often involved in severe infections, in which the effects of bacterial
virulence factors have great importance. Antistaphylococcal regimens should take into …

Activation of the NLRP3-inflammasome contributes to Staphylococcus aureus PVL-
associated diseases, such as necrotizing pneumonia. The Staphylococcus aureus pore …

Although azithromycin is extensively used in the treatment of respiratory tract infections as
well as skin and skin-related infections, pharmacokinetics of azithromycin in extracellular …

Tuberculosis (TB) is an infectious disease caused by an obligate intracellular pathogen,
Mycobacterium tuberculosis (M. tb) and is responsible for the maximum number of deaths …

While antibiotics are clearly important treatments for infection, antibiotic-induced modulation
of the immune system can have detrimental effects on pathogen clearance and immune …

Background With the widespread use of tigecycline, especially in elderly people infected
with multidrug-resistant bacteria, the associated coagulation disorders are attracting the …

Staphylococcal enterotoxin B (SEB) and related bacterial toxins cause diseases in humans
and laboratory animals ranging from food poisoning, acute lung injury to toxic shock. These …

Sepsis, a serious cause of morbidity in humans, has no proper single medication dedicated
to it. In this review, we look at the current treatment modalities, the different approaches …

Protein synthesis inhibitor antibiotics inhibit synthesis of new proteins, including exotoxins
and other important virulence determinants in Staphylococcus aureus. A summary of the …