Polysaccharide-encapsulated organisms are the leading cause of bacterial meningitis and
pneumonia in children. The use of protein–polysaccharide conjugate vaccines in developed …

Meningococcal C conjugate vaccine was introduced in the UK in November 1999 together
with a comprehensive meningococcal surveillance strategy to support and inform the …

Meningococcal serogroup C conjugate (MCC) vaccines were licensed in the United
Kingdom more than 10 years ago based on correlates of protection that had previously been …

The world's poorest children are likely to be malnourished when receiving their childhood
vaccines. It is uncertain whether this affects vaccine efficacy and whether the …

The Global Meningococcal Initiative (GMI) is composed of an international group of
scientists, clinicians and public health officials with expertise in meningococcal immunology …

Invasive meningococcal disease (IMD) is a life-threatening, unpredictable condition.
Vaccines are available against 5 of the 6 meningococcal serogroups (Men) accounting for …

BACKGROUND: Neisseria meningitidis serogroup B (MnB) is a leading cause of bacterial
meningitis and septicemia in adolescents and young adults. No currently licensed and …

Introduction: Globally, the three main pathogens causing serious infections are
Haemophilus influenzae type b, Streptococcus pneumoniae and Neisseria meningitidis …

Background. Neisseria meningitidis is an important cause of invasive bacterial infection in
the United States, and disease rates are higher for adolescents than for the general …

Polysaccharides are often the most abundant antigens found on the extracellular surfaces of
bacterial cells. These polysaccharides play key roles in interactions with the outside world …