A review on recent advances in nitrogen-containing molecules and their biological applications

N Kerru, L Gummidi, S Maddila, KK Gangu… - Molecules, 2020 - mdpi.com
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …

A comprehensive review on the biological interest of quinoline and its derivatives

BS Matada, R Pattanashettar, NG Yernale - Bioorganic & Medicinal …, 2021 - Elsevier
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Green recipes to quinoline: A review

LM Nainwal, S Tasneem, W Akhtar, G Verma… - European Journal of …, 2019 - Elsevier
The quinoline core possesses a vast number of biological activities such as anticancer,
antimalarial, antimicrobial, antifungal, antitubercular and antileishmanial. The conventional …

Synthetic and medicinal perspective of quinolines as antiviral agents

R Kaur, K Kumar - European Journal of Medicinal Chemistry, 2021 - Elsevier
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …

Tandem construction of biological relevant aliphatic 5-membered N-heterocycles

D Łowicki, P Przybylski - European Journal of Medicinal Chemistry, 2022 - Elsevier
Nature often uses cascade reactions in a highly stereocontrolled manner for assembly
structurally diverse nitrogen-containing heterocyclic scaffolds, ie secondary metabolites …

Recent advances in metal-free quinoline synthesis

GA Ramann, BJ Cowen - Molecules, 2016 - mdpi.com
The quinoline ring system is one of the most ubiquitous heterocycles in the fields of
medicinal and industrial chemistry, forming the scaffold for compounds of great significance …

Quinoline-based metal complexes: Synthesis and applications

R Kumar, A Thakur, D Chandra, AK Dhiman… - Coordination Chemistry …, 2024 - Elsevier
Quinoline-based metal complexes have gained considerable attention in recent years due
to their applications in various fields, including catalysis, material sciences, and medicinal …

Oxidative Annulations Involving DMSO and Formamide: K2S2O8 Mediated Syntheses of Quinolines and Pyrimidines

SD Jadhav, A Singh - Organic letters, 2017 - ACS Publications
An efficient strategy toward 4-arylquinolines and 4-arylpyrimidines from readily available
precursors is described. Oxidative annulation promoted by K2S2O8 involving anilines, aryl …

Recent advances and prospects in the metal-free synthesis of quinolines

NA Harry, SM Ujwaldev, G Anilkumar - Organic & Biomolecular …, 2020 - pubs.rsc.org
Quinolines are a predominant class of nitrogen containing heterocycles with wide
applications in the medical and industrial fields. Owing to their significant importance …

Recent developments in the synthesis of nitrogen-containing heterocycles from β-aminovinyl esters/ketones as C [double bond, length as m-dash] C–N donors

XF Xia, YN Niu - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Nitrogen-containing heterocycles are ubiquitous fragments of numerous natural products,
pharmaceuticals, designed bioactive drug candidates and agrochemicals. During the past …