Immobilization of pectinase on chitosan-alginate-clay composite beads: Experimental, DFT and molecular docking studies
A Aksu, S Çetinkaya, AF Yenidünya, ŞA Çetinus… - Journal of Molecular …, 2023 - Elsevier
Pectinase was immobilized on chitosan-alginate-clay (CAC) beads using epichlorohydrin
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …
Isofraxidin: Antioxidant, Anti‐carbonic Anhydrase, Anti‐cholinesterase, Anti‐diabetic, and in Silico Properties
The development of innovative pharmacological formulations for the treatment and
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto …
Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been
synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay …
synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay …
Review and perspective on bioinformatics tools using machine learning and deep learning for predicting antiviral peptides
Viruses constitute a constant threat to global health and have caused millions of human and
animal deaths throughout human history. Despite advances in the discovery of antiviral …
animal deaths throughout human history. Despite advances in the discovery of antiviral …
Novel Quinazolinone Derivatives: Potential Synthetic Analogs for the Treatment of Glaucoma, Alzheimer's Disease and Diabetes Mellitus
Quinazolinones, which represent an important part of nitrogen‐containing six‐membered
heterocyclic compounds, are frequently used in drug design due to their wide biological …
heterocyclic compounds, are frequently used in drug design due to their wide biological …
Synthesis of new carboxylates and sulfonates containing thiazolidin-4-one ring and evaluation of inhibitory properties against some metabolic enzymes
A series of thizaolidin-4-one derivatives (3a-o) was synthesized with excellent yield (94–
97%) and the structures of the compounds were characterized with Fourier-transform …
97%) and the structures of the compounds were characterized with Fourier-transform …
Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
In the present work, a series of compounds containing imidazole and hydrazone structural
frameworks were synthesized and characterized using various spectral techniques …
frameworks were synthesized and characterized using various spectral techniques …
Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation
B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …
Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods
A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
A complete investigation to understand the pathways that could be affected by glycyrrhizin
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …
Antioxidant enzyme activities, molecular docking studies, MM-GBSA, and molecular dynamic of chlorpyrifos in freshwater fish Capoeta umbla
Chlorpyrifos (CPF), which was started to be used in 1965, is a broad spectrum
organophosphate insecticide that is used more and more day by day. Commonly used to …
organophosphate insecticide that is used more and more day by day. Commonly used to …