Autophagy is a fast-moving field with an enormous impact on human health and disease.
Understanding the complexity of the mechanism and regulation of this process often benefits …

Dictyostelium discoideum offers unique advantages for studying fundamental cellular
processes, host–pathogen interactions as well as the molecular causes of human diseases …

Dictyostelium discoideum is one of eight non‐mammalian model organisms recognized by
the National Institute of Health for the study of human pathology. The use of this slime mould …

Macroendocytosis comprising phagocytosis and macropinocytosis is an actin-driven
process regulated by small GTPases that depend on the dynamic reorganization of the …

Actin filaments play an essential role in cell movement, and many posttranslational
modifications regulate actin filament assembly. Here we report that prolyl hydroxylase 3 …

The social amoeba Dictyostelium discoideum has long served as a model system for
studying fundamental processes in cell and developmental biology. This eukaryotic microbe …

Dictyostelid social amoebae are a large and ancient group of soil microbes with an unusual
multicellular stage in their life cycle. Taxonomically, they belong to the eukaryotic …

Collective cell movement is a key component of many important biological processes,
including wound healing, the immune response and the spread of cancers. To understand …

Cell motility is a central process involved in fundamental biological phenomena during
embryonic development, wound healing, immune surveillance, and cancer spreading. Cell …

In multicellular organisms, cell motility is central in all morphogenetic processes, tissue
maintenance, wound healing and immune surveillance. Hence, the control of cell motion is a …