Conspectus Sialic acids are fascinating negatively charged nine-carbon monosaccharides.
Sialic acid-containing glycans and glycoconjugates are structurally diverse, functionally …

Glycosphingolipids (GSLs) are major amphiphilic glycolipids present on the surface of living
cell membranes. They have important biological functions, including maintaining plasma …

Disialosyl globopentaosylceramide (DSGb5) is a tumor-associated complex
glycosphingolipid. However, the accessibility of structurally well-defined DSGb5 for precise …

Natural products, with their array of structural complexity, diversity, and biological activity,
have inspired generations of chemists and driven the advancement of techniques in their …

While the field of biocatalysis has bloomed over the past 20–30 years, advances in the
understanding and improvement of carbohydrate-active enzymes, in particular, the sugar …

Glycomonomers having N-glycosidic linkages were prepared from a known glycosyl amine,
N-acetyl-d-glucosamine (GlcNAc). Radical polymerization of the glycomonomers gave a …

Large‐scale synthesis of GM1, an important ganglioside in mammalian cells especially
those in the nervous system, is needed to explore its therapeutic potential. Biocatalytic …

In nature, almost all cells are covered with a complex array of glycan chain namely sialic
acids or nuraminic acids, a negatively charged nine carbon sugars which is considered for …

Chemo-enzymatic synthesis is spot on for ganglioside glycan libraries | Nature Chemistry
Skip to main content Thank you for visiting nature.com. You are using a browser version …

To accelerate the biological study and application of the diverse functions of
glycosphingolipids (GSLs), the production of structurally defined GSLs has been greatly …