Eph receptors and ephrins in cancer: bidirectional signalling and beyond

EB Pasquale - Nature Reviews Cancer, 2010 - nature.com
The Eph receptor tyrosine kinases and their ephrin ligands have intriguing expression
patterns in cancer cells and tumour blood vessels, which suggest important roles for their …

EMT in cervical cancer: its role in tumour progression and response to therapy

R Qureshi, H Arora, MA Rizvi - Cancer letters, 2015 - Elsevier
The prognosis of cervical patients significantly decreases as the cancer metastasizes to
other parts of the body. The epithelial to mesenchymal transition (EMT) plays an important …

Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas

RF Barth, B Kaur - Journal of neuro-oncology, 2009 - Springer
In this review we will describe eight commonly used rat brain tumor models and their
application for the development of novel therapeutic and diagnostic modalities. The C6, 9L …

The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting

J Wykosky, W Debinski - Molecular Cancer Research, 2008 - AACR
The Eph receptor tyrosine kinases and ephrin ligands have been studied extensively for
their roles in developmental processes. In recent years, Eph receptors and ephrins have …

[HTML][HTML] C6 cell line: The gold standard in glioma research

D Giakoumettis, A Kritis, N Foroglou - Hippokratia, 2018 - ncbi.nlm.nih.gov
Background: Glioblastoma multiforme is the most aggressive brain tumor with poor
prognosis and an average survival of 1-2 years. Animal models that simulate the features of …

Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cells

Y Lu, F Jiang, H Jiang, K Wu, X Zheng, Y Cai… - European journal of …, 2010 - Elsevier
Gallic acid, an organic acid, also known as 3, 4, 5-trihydroxybenzoic acid, is cytotoxic
against certain cancer cells, without harming normal cells. The objective of this study is to …

Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis

F Winkler, Y Kienast, M Fuhrmann, L Von Baumgarten… - Glia, 2009 - Wiley Online Library
Infiltration of cancer cells into normal tissue is a hallmark of malignant gliomas and
compromises treatment options. A lack of appropriate models limits the study of this invasion …

An experimenter's guide to glioblastoma invasion pathways

MC de Gooijer, MG Navarro, R Bernards… - Trends in molecular …, 2018 - cell.com
Glioblastoma is a highly aggressive brain tumor that is characterized by its unparalleled
invasiveness. Invasive glioblastoma cells not only escape surgery and focal therapies but …

The role of the Eph receptor family in tumorigenesis

M Anderton, E van der Meulen, MJ Blumenthal… - Cancers, 2021 - mdpi.com
Simple Summary The Eph receptor family is implicated in both tumour promotion and
suppression, depending on the tissue-specific context of available receptor interactions with …

Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy

L Teng, M Nakada, SG Zhao, Y Endo… - British journal of …, 2011 - nature.com
Background: Recurrence of glioma frequently occurs within the marginal area of the surgical
cavity due to invading residual cells. 5-Aminolevulinic acid (5-ALA) fluorescence-guided …