Angiosarcoma is a rare endothelial-derived malignancy that is extremely diverse in
anatomy, aetiology, molecular and immune characteristics. While novel therapeutic …

The landscape of tissue-based imaging modalities is constantly and rapidly evolving. While
formalin-fixed, paraffin-embedded material is still useful for histological imaging, the fixation …

Tumor cells reprogram their metabolism to produce specialized metabolites that both fuel
their own growth and license tumor immune evasion. However, the relationships between …

Prediabetes and colorectal cancer (CRC) represent compelling health burdens responsible
for high mortality and morbidity rates, sharing several modifiable risk factors. It has been …

Despite significant advancements in prevention and treatment, colorectal cancer (CRC)
remains the third leading cause of cancer-related deaths. Animal models have emerged as …

This integrative review aims to highlight the importance of investigating the functional role of
AHCYL1, also known as IRBIT, in cancer cells. It has recently been suggested that AHCYL1 …

TET-family members play a critical role in cell fate commitment. Indeed, TET3 is essential to
postnatal development due to yet unknown reasons. To define TET3 function in cell …

Pancreatic cancer is characterized by the prevalence of oncogenic mutations in KRAS.
Previous studies have reported that altered KRAS gene dosage drives progression and …

The gut epithelium protects the host from a potentially hostile environment while allowing
nutrient uptake that is vital for the organism. To maintain this delicate task, the gut epithelium …

Abstract Background Methionine (Met) uptake and metabolism are integral to various
cellular functions. Excessive intake of Met from human diets can lead to numerous health …