[HTML][HTML] Transgenic fluorescent zebrafish lines that have revolutionized biomedical research
CP Choe, SY Choi, Y Kee, MJ Kim, SH Kim… - Laboratory Animal …, 2021 - Springer
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …
vertebrate model organism in more than 40,000 biomedical research studies. Especially …
Zebrafish: an emerging model for orthopedic research
Advances in next‐generation sequencing have transformed our ability to identify genetic
variants associated with clinical disorders of the musculoskeletal system. However, the …
variants associated with clinical disorders of the musculoskeletal system. However, the …
Ancient origin of lubricated joints in bony vertebrates
Synovial joints are the lubricated connections between the bones of our body that are
commonly affected in arthritis. It is assumed that synovial joints first evolved as vertebrates …
commonly affected in arthritis. It is assumed that synovial joints first evolved as vertebrates …
[HTML][HTML] Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population
The Thoroughbred horse is a highly valued domestic animal population under strong
selection for athletic phenotypes. Here we present a high resolution genomics-based …
selection for athletic phenotypes. Here we present a high resolution genomics-based …
Genetically engineered zebrafish as models of skeletal development and regeneration
Zebrafish (Danio rerio) are aquatic vertebrates with significant homology to their terrestrial
counterparts. While zebrafish have a centuries-long track record in developmental and …
counterparts. While zebrafish have a centuries-long track record in developmental and …
Programmed conversion of hypertrophic chondrocytes into osteoblasts and marrow adipocytes within zebrafish bones
Much of the vertebrate skeleton develops from cartilage templates that are progressively
remodeled into bone. Lineage tracing studies in mouse suggest that chondrocytes within …
remodeled into bone. Lineage tracing studies in mouse suggest that chondrocytes within …
Fox proteins are modular competency factors for facial cartilage and tooth specification
P Xu, B Balczerski, A Ciozda, K Louie… - …, 2018 - journals.biologists.com
Facial form depends on the precise positioning of cartilage, bone, and tooth fields in the
embryonic pharyngeal arches. How complex signaling information is integrated to specify …
embryonic pharyngeal arches. How complex signaling information is integrated to specify …
Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation
The specification of cartilage requires Sox9, a transcription factor with broad roles for
organogenesis outside the skeletal system. How Sox9 and other factors gain access to …
organogenesis outside the skeletal system. How Sox9 and other factors gain access to …
[HTML][HTML] Competition between Jagged-Notch and Endothelin1 signaling selectively restricts cartilage formation in the zebrafish upper face
The intricate shaping of the facial skeleton is essential for function of the vertebrate jaw and
middle ear. While much has been learned about the signaling pathways and transcription …
middle ear. While much has been learned about the signaling pathways and transcription …
Understanding the development of oral epithelial organs through single cell transcriptomic analysis
Q Ye, A Bhojwani, JK Hu - Development, 2022 - journals.biologists.com
During craniofacial development, the oral epithelium begins as a morphologically
homogeneous tissue that gives rise to locally complex structures, including the teeth …
homogeneous tissue that gives rise to locally complex structures, including the teeth …