Currently, the treatment and care of diabetic wounds, which generally possess the
characteristics of a high amputation rate, high recurrence rate and high mortality, has …

Obesity is a global epidemic representing a serious public health burden as it is a major risk
factor for the development of cardiovascular disease, stroke and all-cause mortality. Chronic …

A wide variety of cell populations, including both immune and endothelial cells, participate in
the pathogenesis of atherosclerosis. Among these groups, macrophages deserve special …

Cardiovascular diseases, the notorious killer, are mainly caused by atherosclerosis (AS)
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …

Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Two vasculitides, giant cell arteritis (GCA) and Takayasu arteritis (TAK), are recognized as
autoimmune and autoinflammatory diseases that manifest exclusively within the aorta and …

The repair of diabetic wound still encounters huge challenges, such as disordered
inflammatory regulation and impaired neovascularization. Here, a pH/ROS/glucose …

Macrophages are involved in the whole process of atherosclerosis, which is characterized
by accumulation of lipid and inflammation. Presently, clinically used lipid-lowering drugs …

A slew of common metabolic disorders, including type 2 diabetes, metabolic dysfunction-
associated steatotic liver disease and steatohepatitis, are exponentially increasing in our …

Macrophages are heterogeneous and plastic cells, able to adapt their phenotype and
functions to changes in the microenvironment. They are involved in several homeostatic …