The regulatory role of microRNAs in EMT and cancer

A Zaravinos - Journal of oncology, 2015 - Wiley Online Library
The epithelial to mesenchymal transition (EMT) is a powerful process in tumor invasion,
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …

Principles of liver regeneration and growth homeostasis

GK Michalopoulos - Comprehensive physiology, 2013 - Wiley Online Library
Liver regeneration is perhaps the most studied example of compensatory growth aimed to
replace loss of tissue in an organ. Hepatocytes, the main functional cells of the liver, manage …

Epithelial–mesenchymal transition-associated miRNAs in ovarian carcinoma, with highlight on the miR-200 family: Prognostic value and prospective role in ovarian …

M Koutsaki, DA Spandidos, A Zaravinos - Cancer letters, 2014 - Elsevier
MicroRNAs (miRNAs) are a family of short ribonucleic acids found to play a pivotal role in
cancer pathogenesis. MiRNAs are crucial in cellular differentiation, growth, stress response …

MicroRNA-21 accelerates hepatocyte proliferation in vitro via PI3K/Akt signaling by targeting PTEN

B Yan-nan, Y Zhao-yan, L Li-xi, X Qing-jie… - … and biophysical research …, 2014 - Elsevier
MicroRNAs (miRNAs) are involved in controlling hepatocyte proliferation during liver
regeneration. In this study, we established the miRNAs-expression patterns of primary …

Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver

J Schug, LB McKenna, G Walton, N Hand, S Mukherjee… - BMC genomics, 2013 - Springer
Background Validation of physiologic miRNA targets has been met with significant
challenges. We employed HITS-CLIP to identify which miRNAs participate in liver …

Cellular and molecular basis of liver regeneration

S Bangru, A Kalsotra - Seminars in cell & developmental biology, 2020 - Elsevier
Recent advances in genetics and genomics have reinvigorated the field of liver
regeneration. It is now possible to combine lineage-tracing with genome-wide studies to …

MicroRNA-Gene Expression Network in Murine Liver during Schistosoma japonicum Infection

P Cai, X Piao, S Liu, N Hou, H Wang, Q Chen - PLoS One, 2013 - journals.plos.org
Background Schistosomiasis japonica remains a significant public health problem in China
and Southeast Asian countries. The most typical and serious outcome of the chronic oriental …

[HTML][HTML] Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis

L de Haan, SJ van der Lely, ALK Warps… - Journal of clinical and …, 2018 - ncbi.nlm.nih.gov
Background Liver regeneration following partial hepatectomy (PHx) is a complicated
process involving multiple organs and several types of signaling networks. The bile acid …

[PDF][PDF] Timed regulation of P‐element‐induced wimpy testis–interacting RNA expression during rat liver regeneration

F Rizzo, A Hashim, G Marchese, M Ravo… - …, 2014 - Wiley Online Library
Small noncoding RNAs comprise a growing family of molecules that regulate key cellular
processes, including messenger RNA (mRNA) degradation, translational repression, and …

MiR-207 inhibits autophagy and promotes apoptosis of cardiomyocytes by directly targeting LAMP2 in type 2 diabetic cardiomyopathy

R Xing, D Liu, X Cheng, X Tian, C Yan, Y Han - … and Biophysical Research …, 2019 - Elsevier
Autophagy dysfunction plays a critical role in diabetic cardiomyopathy (DCM). MiR-207
regulates the expression of lysosomal-associated membrane protein 2 (LAMP2), an …