Liver regeneration is perhaps the most studied example of compensatory growth aimed to replace loss of tissue in an organ. Hepatocytes, the main functional cells of the liver, manage …
MicroRNAs (miRNAs) are a family of short ribonucleic acids found to play a pivotal role in cancer pathogenesis. MiRNAs are crucial in cellular differentiation, growth, stress response …
B Yan-nan, Y Zhao-yan, L Li-xi, X Qing-jie… - … and biophysical research …, 2014 - Elsevier
MicroRNAs (miRNAs) are involved in controlling hepatocyte proliferation during liver regeneration. In this study, we established the miRNAs-expression patterns of primary …
J Schug, LB McKenna, G Walton, N Hand, S Mukherjee… - BMC genomics, 2013 - Springer
Background Validation of physiologic miRNA targets has been met with significant challenges. We employed HITS-CLIP to identify which miRNAs participate in liver …
S Bangru, A Kalsotra - Seminars in cell & developmental biology, 2020 - Elsevier
Recent advances in genetics and genomics have reinvigorated the field of liver regeneration. It is now possible to combine lineage-tracing with genome-wide studies to …
P Cai, X Piao, S Liu, N Hou, H Wang, Q Chen - PLoS One, 2013 - journals.plos.org
Background Schistosomiasis japonica remains a significant public health problem in China and Southeast Asian countries. The most typical and serious outcome of the chronic oriental …
L de Haan, SJ van der Lely, ALK Warps… - Journal of clinical and …, 2018 - ncbi.nlm.nih.gov
Background Liver regeneration following partial hepatectomy (PHx) is a complicated process involving multiple organs and several types of signaling networks. The bile acid …
Small noncoding RNAs comprise a growing family of molecules that regulate key cellular processes, including messenger RNA (mRNA) degradation, translational repression, and …
R Xing, D Liu, X Cheng, X Tian, C Yan, Y Han - … and Biophysical Research …, 2019 - Elsevier
Autophagy dysfunction plays a critical role in diabetic cardiomyopathy (DCM). MiR-207 regulates the expression of lysosomal-associated membrane protein 2 (LAMP2), an …