Reconstructing early microbial life

B Kaçar - Annual Review of Microbiology, 2024 - annualreviews.org
For more than 3.5 billion years, life experienced dramatic environmental extremes on Earth.
These include shifts from oxygen-less to overoxygenated atmospheres and cycling between …

Toward a natural history of microbial life

C Magnabosco, F Husain, MM Paoletti… - Annual Review of …, 2024 - annualreviews.org
For most of Earth's history life was microbial, with archaeal and bacterial cells mediating
biogeochemical cycles through their metabolisms and ecologies. This diversity was …

An Overview of Exoplanet Biosignatures

EW Schwieterman, M Leung - Reviews in Mineralogy …, 2024 - pubs.geoscienceworld.org
In the last three decades, knowledge of planetary systems other than our own has increased
rapidly with the discovery of over 5,000 exoplanets (Christiansen 2022). These worlds vary …

Discovering genotype–phenotype relationships with machine learning and the Visual Physiology Opsin Database (VPOD)

SA Frazer, M Baghbanzadeh, A Rahnavard… - …, 2024 - academic.oup.com
Background Predicting phenotypes from genetic variation is foundational for fields as
diverse as bioengineering and global change biology, highlighting the importance of …

Transforming yeast into a facultative photoheterotroph via expression of vacuolar rhodopsin

A Peterson, C Baskett, WC Ratcliff, A Burnetti - Current Biology, 2024 - cell.com
Phototrophic metabolism, the capture of light for energy, was a pivotal biological innovation
that greatly increased the total energy available to the biosphere. Chlorophyll-based …

The evolutionary kaleidoscope of rhodopsins

PA Bulzu, VS Kavagutti, AS Andrei, R Ghai - Msystems, 2022 - Am Soc Microbiol
Rhodopsins are widely distributed across all domains of life where they perform a plethora
of functions through the conversion of electromagnetic radiation into physicochemical …

Origin of the Difference in Proton Transport Direction between Inward and Outward Proton-Pumping Rhodopsins

T Urui, Y Mizutani - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus Active transport is a vital and ubiquitous process in biological phenomena. Ion-
pumping rhodopsins are light-driven active ion transporters that share a heptahelical …

Using light for energy: examining the evolution of phototrophic metabolism through synthetic construction

A Peterson, C Baskett, WC Ratcliff, A Burnetti - bioRxiv, 2022 - biorxiv.org
The origin of phototrophy was pivotal in increasing the size and scale of the biosphere, as it
allowed organisms to utilize light-driven energy transport to drive biological processes …

Role of horizontal gene transfers and microbial ecology in the evolution of fluxes through the tricarboxylic acid cycle

T Sokolskyi, S DasSarma - International Journal of Astrobiology, 2023 - cambridge.org
The origin of carbon fixation is a fundamental question in astrobiology. While the Calvin
cycle is the most active on the modern Earth, the reductive tricarboxylic acid (TCA) cycle …

Foundations for reconstructing early microbial life

B Kacar - arXiv preprint arXiv:2406.09354, 2024 - arxiv.org
For more than 3.5 billion years, life experienced dramatic environmental extremes on Earth.
These include shifts from oxygen-less to over-oxygenated atmospheres and cycling …