Physics and biology of ultrahigh dose-rate (FLASH) radiotherapy: a topical review

N Esplen, MS Mendonca… - Physics in Medicine & …, 2020 - iopscience.iop.org
Ultrahigh dose-rate radiotherapy (RT), or'FLASH'therapy, has gained significant momentum
following various in vivo studies published since 2014 which have demonstrated a reduction …

A review of recent progress on laser-plasma acceleration at kHz repetition rate

J Faure, D Gustas, D Guénot, A Vernier… - Plasma Physics and …, 2018 - iopscience.iop.org
We report on recent progress on laser-plasma acceleration using a low energy and high-
repetition rate laser system. Using only few milliJoule laser energy, in conjunction with …

Sub-cycle millijoule-level parametric waveform synthesizer for attosecond science

GM Rossi, RE Mainz, Y Yang, F Scheiba… - Nature …, 2020 - nature.com
The availability of high-energy pulses with durations shorter than the period of their carrier
frequency (sub-cycle) will reveal new regimes of strong-field light–matter interactions …

Relativistic-intensity near-single-cycle light waveforms at kHz repetition rate

M Ouillé, A Vernier, F Böhle, M Bocoum… - Light: Science & …, 2020 - nature.com
The development of ultra-intense and ultra-short light sources is currently a subject of
intense research driven by the discovery of novel phenomena in the realm of relativistic …

Laser-accelerated, low-divergence 15-MeV quasimonoenergetic electron bunches at 1 kHz

F Salehi, M Le, L Railing, M Kolesik, HM Milchberg - Physical Review X, 2021 - APS
We demonstrate laser wakefield acceleration of quasimonoenergetic electron bunches up to
15 MeV at 1-kHz repetition rate with 2.5-pC charge per bunch and a core with< 7-mrad …

Nonlinear pulse compression of a 200 mJ and 1 kW ultrafast thin-disk amplifier

Y Pfaff, G Barbiero, M Rampp, S Klingebiel, J Brons… - Optics express, 2023 - opg.optica.org
We present a high-energy laser source consisting of an ultrafast thin-disk amplifier followed
by a nonlinear compression stage. At a repetition rate of 5 kHz, the drive laser provides a …

Gev-scale accelerators driven by plasma-modulated pulses from kilohertz lasers

O Jakobsson, SM Hooker, R Walczak - Physical Review Letters, 2021 - APS
We describe a new approach for driving GeV-scale plasma accelerators with long laser
pulses. We show that the temporal phase of a long, high-energy driving laser pulse can be …

Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures

AE Hussein, N Senabulya, Y Ma, MJV Streeter… - Scientific reports, 2019 - nature.com
Laser-wakefield accelerators (LWFAs) are high acceleration-gradient plasma-based particle
accelerators capable of producing ultra-relativistic electron beams. Within the strong …

Demonstration of stable long-term operation of a kilohertz laser-plasma accelerator

L Rovige, J Huijts, I Andriyash, A Vernier… - … Review Accelerators and …, 2020 - APS
We report on the stable and continuous operation of a kilohertz laser-plasma accelerator.
Electron bunches with 2.6 pC charge and 2.5 MeV peak energy were generated via injection …

Optical waveform synthesis and its applications

G Cirmi, RE Mainz, MA Silva‐Toledo… - Laser & Photonics …, 2023 - Wiley Online Library
The quest for ever‐shorter optical pulses has been ongoing for over half a century. Although
few‐cycle pulses have been generated for nearly 40 years, pulse lengths below the single …