Mesenchymal stromal cells induce inhibitory effects on hepatocellular carcinoma through various signaling pathways

J Ai, N Ketabchi, J Verdi, N Gheibi… - Cancer Cell …, 2019 - Springer
Hepatocellular carcinoma (HCC) is the most prevalent type of malignant liver disease
worldwide. Molecular changes in HCC collectively contribute to Wnt/β-catenin, as a tumor …

Mouse models of hepatocellular carcinoma: classification, advancement, and application

S Liu, F Huang, G Ru, Y Wang, B Zhang, X Chen… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the subtype of liver cancer with the highest incidence,
which is a heterogeneous malignancy with increasing incidence rate and high mortality. For …

Feature selection with the Fisher score followed by the Maximal Clique Centrality algorithm can accurately identify the hub genes of hepatocellular carcinoma

C Li, J Xu - Scientific reports, 2019 - nature.com
This study aimed to select the feature genes of hepatocellular carcinoma (HCC) with the
Fisher score algorithm and to identify hub genes with the Maximal Clique Centrality (MCC) …

Preclinical mouse models of hepatocellular carcinoma: An overview and update

CY Gu, TKW Lee - Experimental cell research, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is by far the most common histological subtype of primary
liver cancer. HCC often originates from chronic liver injuries and inflammation, subsequently …

Application of perinatal derivatives on oncological preclinical models: a review of animal studies

R Teixo, AS Pires, E Pereira, B Serambeque… - International journal of …, 2022 - mdpi.com
The increasing cancer incidence has certified oncological management as one of the most
critical challenges for the coming decades. New anticancer strategies are still needed …

[HTML][HTML] Novel combination of mesenchymal stem cell-conditioned medium with sorafenib have synergistic antitumor effect of hepatocellular carcinoma cells

I Seyhoun, S Hajighasemlou, J Ai… - Asian Pacific Journal …, 2019 - ncbi.nlm.nih.gov
Objective: Hepatocellular carcinoma (HCC) is the most common liver malignancy. Sorafenib
is the first-line systemic treatment for advanced HCCs. However, due to safety concerns …

Sorafenib and mesenchymal stem cell therapy: a promising approach for treatment of HCC

S Hajighasemlou, M Nikbakht, S Pakzad… - Evidence‐Based …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most commonly diagnosed cancer and the
second most common cause of cancer‐related death worldwide. Sorafenib (Sora) is used as …

[HTML][HTML] Correlations between stemness indices for hepatocellular carcinoma, clinical characteristics, and prognosis

J Li, C Zhang, X Yuan, Z Ren, Z Yu - American Journal of …, 2020 - ncbi.nlm.nih.gov
Recent studies have shown that cancer stem cells (CSCs) are involved in the occurrence
and development of hepatocellular carcinoma (HCC). However, potential mechanisms for …

Validation and utility of HepG2 xenograft model for hepatocellular carcinoma

Y Song, Q Lu, D Jiang, X Lan - European Journal of Nuclear Medicine and …, 2023 - Springer
We thank Li's comments and interest in our recent article [1]. After careful authentication of
the HepG2 cell line used in our study, we believe the raised concerns regarding possible …

Anti‐inflammatory effect of mesenchymal stem cells on hepatocellular carcinoma in the xenograft mice model

S Hajighasemlou, M Nikbakht, S Pakzad… - Veterinary Medicine …, 2022 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is the fifth most diagnosed cancer and the
second leading cause of cancer‐related deaths worldwide. Sorafenib is the standard …