A new series of aza-indeno [1, 2-b] pyridin-5-one derivatives 6a-h was designed. The novel
pyridin-5-one derivatives were constructed via cyclization of their corresponding hydrazonal …

A general strategy was developed for the synthesis of new fully decorated sulfonyl1, 2, 3-
triazolyl pyrimidines (6a–6j and 8a–8f) from 2-((6-methyl-2-(methylsulfonyl) pyrimidin-4-yl) …

Two series of heterocyclic steroidal pyrazolo [1, 5-a] pyrimidines derived from
dehydroepiandrosterone (DHEA) and epiandrosterone (EPIA) were designed and …

Background/Objectives: Supported by a comparative study between conventional, grinding,
and microwave techniques, a mild and versatile method based on the [1+ 3] cycloaddition of …

New derivatives of tropane scaffold were prepared from the reaction of their thione or
thioamide derivatives with α-halocarbonyl compounds. The structures of all new derivatives …

Background A leading procedure for creating innovative anticancer treatments that, in
theory, can address many of the pharmacokinetic drawbacks of conventional anticancer …

In an attempt to improve and develop biologically potential anticancer agents, synthesis of
new anticancer agents are in progress. This study focused on the synthesis of novel …

The current work highlights the preparation and antitumor activity of new benzimidazole
derivatives of the natural product vanillin as a novel aromatase inhibitor. All the newly …

In this context, we synthesized a novel series of fluorinated-indeno [1, 2-b] pyridin-5-one
derivatives 6a-h and used spectral and elemental studies to demonstrate their structural …

Since arising in 2019, COVID 19 has been causing rapidly-increasing mortality and
morbidity rates across the globe. Herein, novel 1, 3-indanedione-thiazole hybrids were …