[HTML][HTML] The use of the soluble receptor for advanced glycation-end products (sRAGE) as a potential biomarker of disease risk and adverse outcomes

JD Erusalimsky - Redox Biology, 2021 - Elsevier
The soluble receptor for advanced glycation end-products (sRAGE) has been classically
considered a sink for pro-inflammatory RAGE ligands and as such has been associated with …

Role of RAGE in Alzheimer's disease

Z Cai, N Liu, C Wang, B Qin, Y Zhou, M Xiao… - Cellular and molecular …, 2016 - Springer
Receptor for advanced glycation end products (RAGE) is a receptor of the immunoglobulin
super family that plays various important roles under physiological and pathological …

Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

Y Yamamoto, M Liang, S Munesue, K Deguchi… - Communications …, 2019 - nature.com
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal
bonding behaviours. Mice lacking secreted oxcytocin (Oxt−/−, Cd38−/−) or its receptor …

Cyclic AMP regulates key features of macrophages via PKA: recruitment, reprogramming and efferocytosis

GL Negreiros-Lima, KM Lima, IZ Moreira, BLO Jardim… - Cells, 2020 - mdpi.com
Macrophages are central to inflammation resolution, an active process aimed at restoring
tissue homeostasis following an inflammatory response. Here, the effects of db-cAMP on …

The effects of agomelatine on endoplasmic reticulum stress related to mitochondrial dysfunction in hippocampus of aging rat model

T Chanmanee, J Wongpun, C Tocharus… - Chemico-Biological …, 2022 - Elsevier
Background Agomelatine, a novel antidepressant, is a melatonin MT receptor agonist and
serotonin 5HT 2C receptor antagonist. In this study, agomelatine was used to investigate the …

Receptor for advanced glycation end-products promotes activation of alveolar macrophages through the NLRP3 Inflammasome/TXNIP axis in acute lung injury

W Lenga Ma Bonda, M Fournet, R Zhai, J Lutz… - International Journal of …, 2022 - mdpi.com
The roles of thioredoxin-interacting protein (TXNIP) and receptor for advanced glycation end-
products (RAGE)-dependent mechanisms of NOD-like receptor family, pyrin domain …

Glycation reaction and the role of the receptor for advanced glycation end-products in immunity and social behavior

N Leerach, A Harashima, S Munesue, K Kimura… - Glycoconjugate …, 2021 - Springer
The receptor for advanced glycation end-products (receptor for AGEs, RAGE) is a pattern
recognition receptor. The interaction of RAGE with its ligands, such as AGEs, S100 proteins …

Vinpocetine reduces carrageenan-induced inflammatory hyperalgesia in mice by inhibiting oxidative stress, cytokine production and NF-κB activation in the paw and …

KW Ruiz-Miyazawa, AC Zarpelon, FA Pinho-Ribeiro… - PLoS …, 2015 - journals.plos.org
Vinpocetine is a safe nootropic agent used for neurological and cerebrovascular diseases.
The anti-inflammatory activity of vinpocetine has been shown in cell based assays and …

Dual nature of RAGE in host reaction and nurturing the mother–infant bond

Y Oshima, A Harashima, S Munesue, K Kimura… - International journal of …, 2022 - mdpi.com
Non-enzymatic glycation is an unavoidable reaction that occurs across biological taxa. The
final products of this irreversible reaction are called advanced glycation end-products …

Isoforskolin and forskolin attenuate lipopolysaccharide‐induced inflammation through TLR4/MyD88/NF‐κB cascades in human mononuclear leukocytes

X Du, R Shi, Y Wang, W Wu, S Sun, Z Dai… - Phytotherapy …, 2019 - Wiley Online Library
The principal active component of isoforskolin (ISOF) is from the plant Coleus forskohlii,
native to China, which has attracted much attention for its biological effects. We hypothesize …