Recent advances in hepatitis B treatment

GM Prifti, D Moianos, E Giannakopoulou, V Pardali… - Pharmaceuticals, 2021 - mdpi.com
Hepatitis B virus infection affects over 250 million chronic carriers, causing more than
800,000 deaths annually, although a safe and effective vaccine is available. Currently used …

[HTML][HTML] The assessment of hepatocellular carcinoma risk in patients with chronic hepatitis B under antiviral therapy

I Varbobitis, GV Papatheodoridis - Clinical and molecular …, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a primary concern for patients with chronic hepatitis B
(CHB). Antiviral therapy has been reasonably the focus of interest for HCC prevention, with …

[HTML][HTML] Taiwan consensus statement on the management of chronic hepatitis B

RN Chien, JH Kao, CY Peng, CH Chen, CJ Liu… - Journal of the Formosan …, 2019 - Elsevier
The experts of Taiwan Association for the Study of Liver (TASL) have actively participated
and led the guidelines on hepatitis B virus (HBV) management by Asian Pacific Association …

[HTML][HTML] Adverse effects of oral antiviral therapy in chronic hepatitis B

B Kayaaslan, R Guner - World journal of hepatology, 2017 - ncbi.nlm.nih.gov
Oral nucleoside/nucleotide analogues (NAs) are currently the backbone of chronic hepatitis
B (CHB) infection treatment. They are generally well-tolerated by patients and safe to use …

Nucleos (t) ide analogues for reducing hepatocellular carcinoma in chronic hepatitis B patients: a systematic review and meta-analysis

X Wang, X Liu, Z Dang, L Yu, Y Jiang, X Wang… - Gut and …, 2019 - pmc.ncbi.nlm.nih.gov
Background/Aims Studies have shown that nucleos (t) ide analogue (NA) treatment can
reduce the risk of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients, but …

[HTML][HTML] Comparison of renal safety and efficacy of telbivudine, entecavir and tenofovir treatment in chronic hepatitis B patients: real world experience

MC Tsai, CH Chen, PL Tseng, CH Hung… - Clinical Microbiology …, 2016 - Elsevier
This study aims to assess the nephrotoxicity and efficacy of tenofovir disoproxil fumarate
(tenofovir), telbivudine and entecavir. A retrospective study of 587 patients with chronic …

Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling

J Chen, D Li - International Immunopharmacology, 2018 - Elsevier
Renal fibrosis yields decreased renal function and is a potent contributor to chronic kidney
disease (CKD). Telbivudine (LdT) is an anti–hepatitis B virus (HBV) drug that has been …

Potential effects of telbivudine and entecavir on renal function: a systematic review and meta-analysis

X Wu, S Cai, Z Li, C Zheng, X Xue, J Zeng, J Peng - Virology journal, 2016 - Springer
Background To assess the potential effects of telbivudine (LdT) and entecavir (ETV) on renal
function in patients with chronic hepatitis B (CHB), we performed a meta-analysis of the …

New therapeutic perspectives in HBV: when to stop NA s

C Pérez‐Cameo, M Pons, R Esteban - Liver International, 2014 - Wiley Online Library
The goal of chronic hepatitis B (CHB) treatment is to achieve seroclearance of HBsAg.
Nucleos (t) ide analogues (NA s) are one of the first‐line treatments for CHB. NA s produce a …

Does nucleos (t) ide analogues treatment affect renal function in chronic hepatitis B patients who have already decreased eGFR? A longitudinal study

MC Tsai, CH Chen, PL Tseng, CH Hung, KW Chiu… - PLoS …, 2016 - journals.plos.org
This study aimed to assess the renal function in chronic hepatitis B (CHB) patients who
received nucleos (t) ide analogues (NAs) therapy using estimated glomerular filtration rate …