The hippocampus contributes to temporal duration memory in the context of event sequences: A cross-species perspective

ACH Lee, S Thavabalasingam, D Alushaj… - Neuropsychologia, 2020 - Elsevier
Although a large body of research has implicated the hippocampus in the processing of
memory for temporal duration, there is an exigent degree of inconsistency across studies …

Preventing and treating PTSD-like memory by trauma contextualization

AS Al Abed, EG Ducourneau, C Bouarab… - Nature …, 2020 - nature.com
Post-traumatic stress disorder (PTSD) is characterized by emotional hypermnesia on which
preclinical studies focus so far. While this hypermnesia relates to salient traumatic cues …

Hippocampal network reorganization underlies the formation of a temporal association memory

MS Ahmed, JB Priestley, A Castro, F Stefanini… - Neuron, 2020 - cell.com
Episodic memory requires linking events in time, a function dependent on the hippocampus.
In" trace" fear conditioning, animals learn to associate a neutral cue with an aversive …

The memory for time and space differentially engages the proximal and distal parts of the hippocampal subfields CA1 and CA3

Z Beer, P Vavra, E Atucha, K Rentzing, HJ Heinze… - PLoS …, 2018 - journals.plos.org
A well-accepted model of episodic memory involves the processing of spatial and non-
spatial information by segregated pathways and their association within the hippocampus …

Parsing neural circuits of fear learning and extinction across basic and clinical neuroscience: Towards better translation

H Namkung, KL Thomas, J Hall, A Sawa - Neuroscience & Biobehavioral …, 2022 - Elsevier
Over the past decades, studies of fear learning and extinction have advanced our
understanding of the neurobiology of threat and safety learning. Animal studies can provide …

Evidence for the incorporation of temporal duration information in human hippocampal long-term memory sequence representations

S Thavabalasingam, EB O'Neil, J Tay… - Proceedings of the …, 2019 - National Acad Sciences
There has been much interest in how the hippocampus codes time in support of episodic
memory. Notably, while rodent hippocampal neurons, including populations in subfield CA1 …

Learning-prolonged maintenance of stimulus information in CA1 and subiculum during trace fear conditioning

T Bai, L Zhan, N Zhang, F Lin, D Saur, C Xu - Cell Reports, 2023 - cell.com
Temporal associative learning binds discontiguous conditional stimuli (CSs) and
unconditional stimuli (USs), possibly by maintaining CS information in the hippocampus …

Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in …

J Wan, L Ma, X Jiao, W Dong, J Lin… - CNS Neuroscience …, 2024 - Wiley Online Library
Aim Repeated exposure to ketamine during the neonatal period in mice leads to cognitive
impairments in adulthood. These impairments are likely caused by synaptic plasticity and …

Celsr2 regulates NMDA receptors and dendritic homeostasis in dorsal CA1 to enable social memory

B Chen, L Wang, X Li, Z Shi, J Duan, J Wei, C Li… - Molecular …, 2024 - nature.com
Social recognition and memory are critical for survival. The hippocampus serves as a central
neural substrate underlying the dynamic coding and transmission of social information. Yet …

Age-related volumetric alterations in hippocampal subiculum region are associated with reduced retention of the “when” memory component

CH Chi, FC Yang, YL Chang - Brain and Cognition, 2022 - Elsevier
Although age-related differences in episodic memory function are well established, the
differential reduction in fine-grain memory components and its underlying hippocampal …