Anticancer potential of coumarin and its derivatives

N Bhattarai, AA Kumbhar, YR Pokharel… - Mini Reviews in …, 2021 - ingentaconnect.com
Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

Copper complexes as anticancer agents

C Marzano, M Pellei, F Tisato… - Anti-Cancer Agents in …, 2009 - ingentaconnect.com
Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is
regarded as one of the most effective drugs, even if severe toxicities and drug resistance …

The wide pharmacological versatility of semicarbazones, thiosemicarba-zones and their metal complexes.

H Beraldo, D Gambino - Mini reviews in medicinal chemistry, 2004 - europepmc.org
The more significant bioactivities of a variety of semicarbazones (anti-protozoa,
anticonvulsant) and thiosemicarbazones (antibacterial, antifungal, antitumoral, antiviral) and …

Bonding and structure trends of thiosemicarbazone derivatives of metals—an overview

TS Lobana, R Sharma, G Bawa, S Khanna - Coordination Chemistry …, 2009 - Elsevier
This review describes the coordination chemistry of thiosemicarbazones and covers all the
metals for which complexes are reported. The coordination compounds of d-block, p-block …

Platinum complexes as anticancer agents

I Kostova - Recent patents on anti-cancer drug discovery, 2006 - ingentaconnect.com
The application of inorganic chemistry to medicine is a rapidly developing field, and novel
therapeutic and diagnostic metal complexes are now having an impact on medical practice …

Anticancer potency of copper (II) complexes of thiosemicarbazones

NK Singh, AA Kumbhar, YR Pokharel… - Journal of Inorganic …, 2020 - Elsevier
Being a structural and catalytic cofactor in a number of biological pathways, copper
accumulates in tumors owing to selective permeability of the cancer cell membranes …

Contribution to the SAR field of metallated and coordination complexes: Studies of the palladium and platinum derivatives with selected thiosemicarbazones as …

AG Quiroga, CN Ranninger - Coordination Chemistry Reviews, 2004 - Elsevier
This article reviews the chemical and antitumoral properties of thiosemicarbazone complex-
based drugs containing platinum (II) or palladium (II). Tetranuclear orthometallated …

Thiosemicarbazones as potent anticancer agents and their modes of action

B Shakya, PN Yadav - Mini Reviews in Medicinal Chemistry, 2020 - ingentaconnect.com
Thiosemicarbazones (TSCs) are a class of Schiff bases usually obtained by the
condensation of thiosemicarbazide with a suitable aldehyde or ketone. TSCs have been the …

Platinum (II) complexes with 2-acetyl pyridine thiosemicarbazone: synthesis, crystal structure, spectral properties, antimicrobial and antitumour activity

D Kovala-Demertzi, MA Demertzis, JR Miller… - Journal of Inorganic …, 2001 - Elsevier
An interesting series of new platinum complexes has been synthesized by the reaction of
Na2PtCl4 with 2-acetyl pyridine thiosemicarbazone, HAcTsc. The new complexes,[Pt …

Effect of terminal N-substitution in 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde thiosemicarbazones on the mode of coordination, structure, interaction with protein …

DS Raja, G Paramaguru, NSP Bhuvanesh… - Dalton …, 2011 - pubs.rsc.org
Four 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde N-substituted thiosemicarbazone ligands
(H2-OQtsc-R, where R= H, Me, Et or Ph) and their corresponding new copper (II) complexes …