Chlamydia (C.) psittaci is an economically relevant pathogen in poultry and pet birds, where
it causes psittacosis/ornithosis, and also a human pathogen causing atypical pneumonia …

Leishmania are protozoan parasites spread by a sandfly insect vector and causing a
spectrum of diseases collectively known as leishmaniasis. The disease is a significant …

Protozoan infections are a serious global health problem,. Natural killer (NK) cells and
cytolytic T lymphocytes (CTLs) eliminate pathogen-infected cells by releasing cytolytic …

CD8+ T cells are crucial for control of a number of medically important protozoan parasites,
including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the …

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical
neglected tropical disease. Specific immunity promotes acute phase survival. Nevertheless …

Leishmaniasis is a neglected disease resulting in a global morbidity of 2,090 thousand
Disability‐Adjusted Life Years and a mortality rate of approximately 60,000 per year. Among …

The kinetics of effector CD8+-T-cell responses to specific Trypanosoma cruzi epitopes was
investigated after challenge. Our results suggest that the delayed kinetics differs from that …

Chagas' disease is a major public health problem affecting nearly 10 million in Latin
America. Despite several experimental vaccines have shown to be immunogenic and …

Interference or competition between CD8+ T cells restricted by distinct MHC-I molecules can
be a powerful means to establish an immunodominant response. However, its importance …

Protection against protozoan parasite Trypanosoma cruzi has been shown to be dependent
on the induction of type 1 immune responses. Replication-deficient human type 5 …