Imaging of lung function using hyperpolarized helium‐3 magnetic resonance imaging: review of current and emerging translational methods and applications
During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …
Pathophysiology of severe asthma: we've only just started
GG King, A James, L Harkness, PAB Wark - Respirology, 2018 - Wiley Online Library
Severe asthma is defined by the high treatment requirements to partly or fully control the
clinical manifestations of disease. It remains a problem worldwide with a large burden for …
clinical manifestations of disease. It remains a problem worldwide with a large burden for …
Asthma and allergic inflammation
RM Locksley - Cell, 2010 - cell.com
Studies of the initiation and maintenance of asthma and allergic inflammation implicate
dysregulated interactions between mucosal epithelia and innate immune cells as the …
dysregulated interactions between mucosal epithelia and innate immune cells as the …
Hyperpolarized 3He and 129Xe MR Imaging in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease
Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
Hyperpolarized 3He magnetic resonance functional imaging semiautomated segmentation
RATIONALE AND OBJECTIVES: To improve intra-and interobserver variability and enable
the use of functional magnetic resonance imaging (MRI) for multicenter, multiobserver …
the use of functional magnetic resonance imaging (MRI) for multicenter, multiobserver …
Mucus Plugs in Asthma at CT Associated with Regional Ventilation Defects at 3He MRI
Background Airway mucus plugs in asthma are associated with exacerbation frequency,
increased eosinophilia, and reduced lung function. The relationship between mucus plugs …
increased eosinophilia, and reduced lung function. The relationship between mucus plugs …
Hyperpolarized 3He and 129Xe MRI: Differences in asthma before bronchodilation
S Svenningsen, M Kirby, D Starr… - Journal of magnetic …, 2013 - Wiley Online Library
Purpose To compare hyperpolarized helium‐3 (3He) and xenon‐129 (129Xe) MRI in
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
CT and Functional MRI to Evaluate AirwayáMucus in Severe Asthma
Background Intraluminal contributor (s) to airflow obstruction in severe asthma are patient-
specific and must be evaluated to personalize treatment. The occurrence and functional …
specific and must be evaluated to personalize treatment. The occurrence and functional …
Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …