Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies
ES Vaz, SV Vassiliades, J Giarolla, MC Polli… - European Journal of …, 2023 - Springer
Introduction Drug repositioning is a strategy to identify a new therapeutic indication for
molecules that have been approved for other conditions, aiming to speed up the traditional …
molecules that have been approved for other conditions, aiming to speed up the traditional …
Protease inhibitors targeting the main protease and papain-like protease of coronaviruses
Introduction The two cysteine proteases from the coronaviruses, which produced deadly
outbreaks in the last two decades, SARS CoV-1/2, and MERS, the main protease (Mpro) and …
outbreaks in the last two decades, SARS CoV-1/2, and MERS, the main protease (Mpro) and …
[HTML][HTML] Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through …
Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus
disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global …
disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global …
[HTML][HTML] Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness …
In view of the potential of traditional plant-based remedies (or phytomedicines) in the
management of COVID-19, the present investigation was aimed at finding novel anti-SARS …
management of COVID-19, the present investigation was aimed at finding novel anti-SARS …
In silico screening of phytopolyphenolics for the identification of bioactive compounds as novel protease inhibitors effective against SARS-CoV-2
M Rudrapal, AR Issahaku, C Agoni… - Journal of …, 2022 - Taylor & Francis
Due to the unavailability specific drugs or vaccines (FDA approved) that can cure COVID-19,
the development of potent antiviral drug candidates/therapeutic molecules against COVID …
the development of potent antiviral drug candidates/therapeutic molecules against COVID …
[HTML][HTML] Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies
The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …
Computational Investigations for Identification of Bioactive Molecules from Baccaurea ramiflora and Bergenia ciliata as Inhibitors of SARS-CoV-2 Mpro
In this study, a hybrid compound library of 72 phytocompounds from two antiviral medicinal
plants (Baccaurea ramiflora and Bergenia ciliata) was computationally investigated for their …
plants (Baccaurea ramiflora and Bergenia ciliata) was computationally investigated for their …
Comparative study of a mathematical epidemic model, statistical modeling, and deep learning for COVID-19 forecasting and management
The COVID-19 pandemic has caused a global crisis with 47,209,305 confirmed cases and
1,209,505 confirmed deaths worldwide as of November 2, 2020. Forecasting confirmed …
1,209,505 confirmed deaths worldwide as of November 2, 2020. Forecasting confirmed …
Adipose-derived, autologous mesenchymal stem cell therapy for patients with post-COVID-19 syndrome: an intermediate-size expanded access program
R Vij, H Kim, H Park, T Cheng, D Lotfi… - Stem Cell Research & …, 2023 - Springer
Background Evolving mutations of the novel coronavirus continue to fuel up the pandemic.
The virus affects the human respiratory system along with other body systems, causing …
The virus affects the human respiratory system along with other body systems, causing …
A blood RNA transcriptome signature for COVID-19
Background COVID-19 is a respiratory viral infection with unique features including a more
chronic course and systemic disease manifestations including multiple organ involvement; …
chronic course and systemic disease manifestations including multiple organ involvement; …