DE Nichols - Pharmacology & therapeutics, 2004 - Elsevier
Hallucinogens (psychedelics) are psychoactive substances that powerfully alter perception, mood, and a host of cognitive processes. They are considered physiologically safe and do …
R Zimmermann, JG Strauss, G Haemmerle… - Science, 2004 - science.org
Mobilization of fatty acids from triglyceride stores in adipose tissue requires lipolytic enzymes. Dysfunctional lipolysis affects energy homeostasis and may contribute to the …
Progressive multifocal leukoencephalopathy (PML) is a rare but often fatal brain disease caused by reactivation of the polyomavirus JC. Knowledge of the characteristics of PML has …
Serotonin, 5-hydroxytryptamine (5-HT), is one of the class of monoamine neurontransmitters, all of which have a chemical template comprised of a basic amino group separated from an …
DA Shapiro, S Renock, E Arrington… - …, 2003 - nature.com
Atypical antipsychotic drugs have revolutionized the treatment of schizophrenia and related disorders. The current clinically approved atypical antipsychotic drugs are characterized by …
BL Roth, K Baner, R Westkaemper… - Proceedings of the …, 2002 - National Acad Sciences
Salvia divinorum, whose main active ingredient is the neoclerodane diterpene Salvinorin A, is a hallucinogenic plant in the mint family that has been used in traditional spiritual …
J Horacek, V Bubenikova-Valesova, M Kopecek… - CNS drugs, 2006 - Springer
Atypical antipsychotics have greatly enhanced the treatment of schizophrenia. The mechanisms underlying the effectiveness and adverse effects of these drugs are, to date, not …
GF Elphick, W Querbes, JA Jordan, GV Gee, S Eash… - Science, 2004 - science.org
The human polyomavirus, JCV, causes the fatal demyelinating disease progressive multifocal leukoencephalopathy in immunocompromised patients. We found that the …
JA Gray, BL Roth - Brain research bulletin, 2001 - Elsevier
5-Hydroxytryptamine2A (serotonin2A, 5-HT2A) receptors are important for many physiologic processes including platelet aggregation, smooth muscle contraction, and the modulation of …