Recent Advancement in Anticancer Compounds from Marine Organisms: Approval, Use and Bioinformatic Approaches to Predict New Targets

G Santaniello, A Nebbioso, L Altucci, M Conte - Marine Drugs, 2022 - mdpi.com
In recent years, the study of anticancer bioactive compounds from marine sources has
received wide interest. Contextually, world regulatory authorities have approved several …

[HTML][HTML] Eribulin in triple negative metastatic breast cancer: critic interpretation of current evidence and projection for future scenarios

L Pizzuti, E Krasniqi, G Barchiesi, M Mazzotta… - Journal of …, 2019 - ncbi.nlm.nih.gov
Triple negative breast cancer (TNBC) is characterized by distinctive biological features that
confer an aggressive clinical behavior. In TNBC patients, the absence of well-defined driver …

Real‐life activity of eribulin mesylate among metastatic breast cancer patients in the multicenter national observational ESME program

W Jacot, P Heudel, J Fraisse, S Gourgou… - … Journal of Cancer, 2019 - Wiley Online Library
Eribulin mesylate (EM) was recently approved for metastatic breast cancer (MBC)
chemotherapy (CT) in late lines by the FDA, with debated results in second line. We …

Effectiveness of eribulin in metastatic breast cancer: 10 years of real-world clinical experience in the United States

SS Mougalian, JK Kish, J Zhang, D Liassou… - Advances in …, 2021 - Springer
Introduction Eribulin was approved in the United States (US) in 2010 for patients with
metastatic breast cancer (MBC) who previously received at least two chemotherapeutic …

Perspectives on the mechanism of action and clinical application of eribulin for metastatic breast cancer

J O'Shaughnessy, V Kaklamani, K Kalinsky - Future Oncology, 2019 - Taylor & Francis
Eribulin is a novel microtubule inhibitor with mitotic and nonmitotic mechanisms of action.
Both pooled and subgroup analyses from large-scale Phase III clinical trials demonstrated …

Feasibility and tolerability of eribulin-based chemotherapy versus other chemotherapy regimens for patients with metastatic triple-negative breast cancer: a single …

W Huang, C Wang, L Wang, Y Shen, Q Chen… - Frontiers in Cell and …, 2024 - frontiersin.org
Background: Patients with Triple-negative breast cancer (TNBC) face a poor prognosis and
limited therapeutic options. Current data on eribulin usage to treat TNBC is scarce …

A phase Ib/II study of eribulin in combination with cyclophosphamide in patients with advanced breast cancer

O Gumusay, LA Huppert, MJM Magbanua… - Breast Cancer Research …, 2024 - Springer
Purpose We hypothesized that eribulin combined with cyclophosphamide (EC) would be an
effective combination with tolerable toxicity for the treatment of advanced breast cancer …

Systematic review of Real-World effectiveness of eribulin for locally advanced or metastatic breast cancer

I Chabot, Q Zhao, Y Su - Current Medical Research and Opinion, 2020 - Taylor & Francis
Background Eribulin mesylate (eribulin) is indicated for patients with metastatic breast
cancer (MBC) who have previously received at least two chemotherapies in the US and for …

[HTML][HTML] Second-line eribulin in triple negative metastatic breast cancer patients. Multicentre retrospective study: the TETRIS trial

E Krasniqi, L Pizzuti, MR Valerio… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Introduction: Large and consistent evidence supports the use of eribulin mesylate in clinical
practice in third or later line treatment of metastatic triple negative breast cancer (mTNBC) …

[HTML][HTML] Efficacy of Eribulin mesylate in older patients with breast cancer: A pooled analysis of clinical trial and real-world data

R Pedersini, P di Mauro, V Amoroso, MC Parati… - Journal of Geriatric …, 2020 - Elsevier
Purpose Eribulin mesylate (EM) is a non-taxane microtubule inhibitor approved for use in
patients with metastatic breast cancer. With this pooled analysis of retrospective studies, we …