Biomolecular condensates, sometimes also known as membraneless organelles (MLOs), can form through weak multivalent intermolecular interactions of proteins and nucleic acids …
BD Freibaum, J Messing, H Nakamura… - Journal of Cell …, 2024 - rupress.org
Stress granule formation is triggered by the release of mRNAs from polysomes and is promoted by the action of the RNA-binding proteins G3BP1/2. Stress granules have been …
Simple Summary The cytoplasm of a living cell is a crowded place, containing hundreds of types of protein and other macromolecules. Cells reliably and continually perform thousands …
J Koch, F Lyko - Current Opinion in Genetics & Development, 2024 - Elsevier
N 6-methyladenosine (m 6 A) is the most abundant internal modification of eukaryotic mRNAs. m 6 A affects the fate of its targets in all aspects of the mRNA life cycle and has …
Viral infections pose a significant health risk worldwide. There is a pressing need for more effective antiviral drugs to combat emerging novel viruses and the reemergence of …
A novel class of protein misfolding characterized by either the formation of non-native noncovalent lasso entanglements in the misfolded structure or loss of native entanglements …
F Tonello - International Journal of Molecular Sciences, 2023 - mdpi.com
Secreted phospholipases of type A2 (sPLA2s) are proteins of 14–16 kDa present in mammals in different forms and at different body sites. They are involved in lipid …