Cis-regulatory sequences in plants: their importance, discovery, and future challenges

RJ Schmitz, E Grotewold, M Stam - The plant cell, 2022 - academic.oup.com
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

Epigenetic regulation of thermomorphogenesis and heat stress tolerance

G Perrella, I Bäurle, M van Zanten - New Phytologist, 2022 - Wiley Online Library
Many environmental conditions fluctuate and organisms need to respond effectively. This is
especially true for temperature cues that can change in minutes to seasons and often follow …

Position-dependent function of human sequence-specific transcription factors

SH Duttke, C Guzman, M Chang, NP Delos Santos… - Nature, 2024 - nature.com
Patterns of transcriptional activity are encoded in our genome through regulatory elements
such as promoters or enhancers that, paradoxically, contain similar assortments of …

[HTML][HTML] Epigenetic regulation of abiotic stress memory: maintaining the good things while they last

V Oberkofler, L Pratx, I Bäurle - Current opinion in plant biology, 2021 - Elsevier
As sessile organisms, plants have evolved sophisticated ways to constantly gauge and
adapt to changing environmental conditions including extremes that may be harmful to their …

Alternative splicing and protein diversity: plants versus animals

S Chaudhary, W Khokhar, I Jabre, ASN Reddy… - Frontiers in plant …, 2019 - frontiersin.org
Plants, unlike animals, exhibit a very high degree of plasticity in their growth and
development and employ diverse strategies to cope with the variations during diurnal cycles …

DNA methylation-linked chromatin accessibility affects genomic architecture in Arabidopsis

Z Zhong, S Feng, SH Duttke… - Proceedings of the …, 2021 - National Acad Sciences
DNA methylation is a major epigenetic modification found across species and has a
profound impact on many biological processes. However, its influence on chromatin …

Chloroplast gene expression: Recent advances and perspectives

Y Zhang, L Tian, C Lu - Plant Communications, 2023 - cell.com
Chloroplasts evolved from an ancient cyanobacterial endosymbiont more than 1.5 billion
years ago. During subsequent coevolution with the nuclear genome, the chloroplast …

The R-loop is a common chromatin feature of the Arabidopsis genome

W Xu, H Xu, K Li, Y Fan, Y Liu, X Yang, Q Sun - Nature plants, 2017 - nature.com
R-loops are functional structures in chromatin comprising one single-stranded DNA and a
DNA: RNA hybrid. Here, we report ssDRIP-seq, a single-strand DNA ligation-based library …

Analysis of genetically diverse macrophages reveals local and domain-wide mechanisms that control transcription factor binding and function

VM Link, SH Duttke, HB Chun, IR Holtman, E Westin… - Cell, 2018 - cell.com
Non-coding genetic variation is a major driver of phenotypic diversity and allows the
investigation of mechanisms that control gene expression. Here, we systematically …

Identification and dynamic quantification of regulatory elements using total RNA

SH Duttke, MW Chang, S Heinz, C Benner - Genome research, 2019 - genome.cshlp.org
The spatial and temporal regulation of transcription initiation is pivotal for controlling gene
expression. Here, we introduce capped-small RNA-seq (csRNA-seq), which uses total RNA …