Metastases, or migration of cancers, are common and severe cancer complications.
Although the 5-year survival rates of primary tumors have greatly improved, those of …

MicroRNAs are non-coding RNAs that serve as regulatory molecules in a variety of
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …

Carcinoma cells undergo epithelial-mesenchymal transition (EMT); however, contributions
of EMT heterogeneity to disease progression remain a matter of debate. Here, we …

Abstract Background Circular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs)
and characterized by covalently closed loop without 5′ and 3′ end. Recently, the …

Metastatic recurrence and postoperative wound infection are two major challenges for
breast cancer patients. In this study, a multifunctional responsive hydrogel system was …

The great advances in the studies on metal complexes for the treatment of different cancer
forms, starting from the pioneering works on platinum derivatives, have fostered an …

Rationale: Tumors are commonly treated by resection, which usually leads to massive
hemorrhage and tumor cell residues, thereby increasing the risk of local recurrence and …

Simple Summary Solid tumors comprise metabolically hostile areas adjacent to
metabolically friendly ones, and their distribution fluctuates in space and time. Selection …

Due to poor T cell infiltration, tumors evade immune surveillance. Increased CD8+ T cell
infiltration in breast cancer suggests a satisfactory response to immunotherapy. COPS6 has …

Here, rational engineering of doxorubicin prodrug loaded peptide-targeted liposomal
nanoparticles to selectively target metastatic breast cancer cells in vivo is described …