Mouse models of glioblastoma for the evaluation of novel therapeutic strategies
Glioblastoma (GBM) is an incurable brain tumor with a median survival of approximately 15
months despite an aggressive standard of care that includes surgery, chemotherapy, and …
months despite an aggressive standard of care that includes surgery, chemotherapy, and …
Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles
The blood–brain barrier represents a significant challenge for the treatment of high-grade
gliomas, and our understanding of drug transport across this critical biointerface remains …
gliomas, and our understanding of drug transport across this critical biointerface remains …
Dissecting and rebuilding the glioblastoma microenvironment with engineered materials
Glioblastoma (GBM) is the most aggressive and common form of primary brain cancer.
Several decades of research have provided great insight into GBM progression; however …
Several decades of research have provided great insight into GBM progression; however …
Rapid 3D bioprinting of glioblastoma model mimicking native biophysical heterogeneity
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor characterized by high
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …
All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model
K Chattrairat, T Yasui, S Suzuki, A Natsume… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) have promising potential as biomarkers for early cancer
diagnosis. The EVs have been widely studied as biological cargo containing essential …
diagnosis. The EVs have been widely studied as biological cargo containing essential …
In vitro glioblastoma models: A journey into the third dimension
M Paolillo, S Comincini, S Schinelli - Cancers, 2021 - mdpi.com
Simple Summary In this review, the thorny issue of glioblastoma models is addressed, with a
focus on 3D in vitro models. In the first part of the manuscript, glioblastoma features and …
focus on 3D in vitro models. In the first part of the manuscript, glioblastoma features and …
Multicellular 3D models to study tumour-stroma interactions
E Colombo, MG Cattaneo - International journal of molecular sciences, 2021 - mdpi.com
Two-dimensional (2D) cell cultures have been the standard for many different applications,
ranging from basic research to stem cell and cancer research to regenerative medicine, for …
ranging from basic research to stem cell and cancer research to regenerative medicine, for …
Ulvan loaded graphene oxide nanoparticle fabricated with chitosan and d-mannose for targeted anticancer drug delivery
S Kesavan, KS Meena, SA Sharmili… - Journal of Drug Delivery …, 2021 - Elsevier
Cancer growth is a developing significant public health threat, and notwithstanding the
advances in biomedical research and innovation, a pressing need is felt for the progress of …
advances in biomedical research and innovation, a pressing need is felt for the progress of …
P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma
R Mehdizadeh, A Madjid Ansari, F Forouzesh… - Scientific reports, 2023 - nature.com
The average survival of patients with glioblastoma is 12–15 months. Therefore, finding a
new treatment method is important, especially in cases that show resistance to treatment …
new treatment method is important, especially in cases that show resistance to treatment …