Criteria for the design of tissue-mimicking phantoms for the standardization of biophotonic instrumentation
A lack of accepted standards and standardized phantoms suitable for the technical
validation of biophotonic instrumentation hinders the reliability and reproducibility of its …
validation of biophotonic instrumentation hinders the reliability and reproducibility of its …
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer
KM Muilenburg, CC Isder, P Radhakrishnan, SK Batra… - Cancer letters, 2023 - Elsevier
Pancreatic cancer is difficult to resect due to its unique challenges, often leading to
incomplete tumor resections. Fluorescence-guided surgery (FGS), also known as …
incomplete tumor resections. Fluorescence-guided surgery (FGS), also known as …
3D printing fluorescent material with tunable optical properties
AJ Ruiz, S Garg, SS Streeter, MK Giallorenzi… - Scientific Reports, 2021 - nature.com
The 3D printing of fluorescent materials could help develop, validate, and translate imaging
technologies, including systems for fluorescence-guided surgery. Despite advances in 3D …
technologies, including systems for fluorescence-guided surgery. Despite advances in 3D …
A guideline for clinicians performing clinical studies with fluorescence imaging
Fluorescence imaging is an emerging imaging technique that has shown many benefits for
clinical care. Currently, the field is in rapid clinical translation, and an unprecedented …
clinical care. Currently, the field is in rapid clinical translation, and an unprecedented …
3D-Printed Tumor Phantoms for Assessment of In Vivo Fluorescence Imaging Analysis Methods
EPM LaRochelle, SS Streeter, EA Littler… - Molecular imaging and …, 2023 - Springer
Purpose Interventional fluorescence imaging is increasingly being utilized to quantify cancer
biomarkers in both clinical and preclinical models, yet absolute quantification is complicated …
biomarkers in both clinical and preclinical models, yet absolute quantification is complicated …
Impact of surgical lights on the performance of fluorescence-guided surgery systems: a pilot study
Simple Summary The use of near-infrared fluorophores has many promising applications in
surgical oncology, both in humans and in pet animals. The reliability of the procedure is …
surgical oncology, both in humans and in pet animals. The reliability of the procedure is …
The impact of temporal variation in indocyanine green administration on tumor identification during fluorescence guided breast surgery
MS Kedrzycki, M Leiloglou, V Chalau… - Annals of Surgical …, 2021 - Springer
Background On average, 21% of women in the USA treated with Breast Conserving Surgery
(BCS) undergo a second operation because of close positive margins. Tumor identification …
(BCS) undergo a second operation because of close positive margins. Tumor identification …
Assessment of open-field fluorescence guided surgery systems: implementing a standardized method for characterization and comparison
Significance Fluorescence guided surgery (FGS) has demonstrated improvements in
decision making and patient outcomes for a wide range of surgical procedures. Not only can …
decision making and patient outcomes for a wide range of surgical procedures. Not only can …
Mapping estimates of vascular permeability with a clinical indocyanine green fluorescence imaging system in experimental pancreatic adenocarcinoma tumors
Significance Pancreatic cancer tumors are known to be avascular, but their neovascular
capillaries are still chaotic leaky vessels. Capillary permeability could have significant value …
capillaries are still chaotic leaky vessels. Capillary permeability could have significant value …
Performance of two clinical fluorescence imaging systems with different targeted and non-targeted near-infrared fluorophores: A cadaveric explorative study
Introduction Near-infrared (NIR) fluorescence-guided surgery is increasingly utilized in
humans and pets. As clinical imaging systems are optimized for Indocyanine green (ICG) …
humans and pets. As clinical imaging systems are optimized for Indocyanine green (ICG) …