High drug-loading nanomedicines: progress, current status, and prospects

S Shen, Y Wu, Y Liu, D Wu - International journal of nanomedicine, 2017 - Taylor & Francis
Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …

Mesoporous silica nanoparticles: Facile surface functionalization and versatile biomedical applications in oncology

R Huang, YW Shen, YY Guan, YX Jiang, Y Wu… - Acta Biomaterialia, 2020 - Elsevier
Mesoporous silica nanoparticles (MSNs) have received increasing interest due to their
tunable particle size, large surface area, stable framework, and easy surface modification …

Internal stimuli-responsive nanocarriers for drug delivery: Design strategies and applications

M Liu, H Du, W Zhang, G Zhai - Materials Science and Engineering: C, 2017 - Elsevier
The design of internal stimuli-responsive nanocarriers has been extensively used for
delivery of various active compounds including drugs, peptides and genes. These …

Progress in mesoporous silica nanoparticles as drug delivery agents for cancer treatment

ED Mohamed Isa, H Ahmad, MB Abdul Rahman… - Pharmaceutics, 2021 - mdpi.com
Cancer treatment and therapy have made significant leaps and bounds in these past
decades. However, there are still cases where surgical removal is impossible, metastases …

Physically stimulus-responsive nanoparticles for therapy and diagnosis

F Farjadian, S Ghasemi, M Akbarian… - Frontiers in …, 2022 - frontiersin.org
Nanoparticles offer numerous advantages in various fields of science, particularly in
medicine. Over recent years, the use of nanoparticles in disease diagnosis and treatments …

Stimuli responsive nanoparticles for controlled anti-cancer drug release

Q Tang, B Yu, L Gao, H Cong… - Current Medicinal …, 2018 - ingentaconnect.com
Conventional drugs used for cancer chemotherapy have severe toxic side effects and show
individually varied therapeutic responses. The convergence of nanotechnology, biology …

Application of non-viral vectors in drug delivery and gene therapy

S Ren, M Wang, C Wang, Y Wang, C Sun, Z Zeng… - Polymers, 2021 - mdpi.com
Vectors and carriers play an indispensable role in gene therapy and drug delivery. Non-viral
vectors are widely developed and applied in clinical practice due to their low …

Delivery of apigenin-loaded magnetic Fe2O3/Fe3O4@ mSiO2 nanocomposites to A549 cells and their antitumor mechanism

R Liu, G Rong, Y Liu, W Huang, D He, R Lu - Materials Science and …, 2021 - Elsevier
This study introduces a mesoporous magnetic nano-system for the delivery of apigenin
(API). A targeted therapeutic drug delivery system was prepared based on Fe 2 O 3/Fe 3 O …

[HTML][HTML] Dual stimuli-responsive mesoporous silica nanoparticles for efficient loading and smart delivery of doxorubicin to cancer with RGD-integrin targeting

HS Kim, JH Kang, JH Jang, EJ Lee, JH Kim… - European Journal of …, 2023 - Elsevier
The recent progress in nanoparticle applications, such as tumor-targeting, has enabled
specific delivery of chemotherapeutics to malignant tissues with enhanced local efficacy …

Hybrid mesoporous silica nanocarriers with thermovalve-regulated controlled release

T Ribeiro, E Coutinho, AS Rodrigues, C Baleizão… - Nanoscale, 2017 - pubs.rsc.org
Mesoporous silica nanoparticles (MSNs) are excellent nanocarriers, featuring very high
cargo capacity due to their large surface area and pore volume. The particle and pore …