Endophytic fungi (EF) are a group of fascinating host-associated fungal communities that
colonize the intercellular or intracellular spaces of host tissues, providing beneficial effects to …

Paclitaxel is a well-known anticancer agent with a unique mechanism of action. It is
considered to be one of the most successful natural anticancer drugs available. This study …

Microbial endophytes are present in all known plant species. The ability to enter and thrive
in the plant tissues makes endophytes unique, showing multidimensional interactions within …

Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …

Endophytic fungi are abundant and have been reported from all tissues such as roots,
stems, leaves, flowers, and fruits. In recent years, research into the beneficial use of …

Endophytes are microbes that inhabit host plants without causing disease and are reported
to be reservoirs of metabolites that combat microbes and other pathogens. Here we review …

Paclitaxel, a tetracyclic diterpenoid compounds, was firstly isolated from the bark of the
Pacific yew trees. Currently, as a low toxicity, high efficiency, and broad-spectrum natural …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

Many reports have been published on bioprospecting of endophytic fungi capable of
producing high value bioactive molecules like, paclitaxel, vincristine, vinblastine …